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GenX - PFOA replacement

Craig Butt
Member

At the Dioxin 2017 conference in Vancouver, BC there were several great presentations about GenX, the PFOA replacement compound produced by Chemours (spinoff company from Dupont).  It appears that interest is rapidly increasing in the scientific and regulatory community.  

Is anyone currently analyzing environmental samples (e.g. water, human serum, wildlife) for GenX?

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Posted : September 22, 2017 1:41 pm
Simon Roberts
Member

Currently, the only supplier of analytical standards for GenX and other emerging PFAS compounds is Wellington Laboratories. Below is a link to the product announcements for GenX, ADONA, and F53B, along with their mass-labelled analogs: 

http://www.well-labs.com/docs/adona_and_f53b_15aug2016_wellington_reporter.pdf

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Posted : September 22, 2017 1:26 pm
Bob Pullano
Member

HI Craig, 

Just seeing this post when looking for another compound of interest.  GEL Laboratories in Charleston SC is currently analyzing GenX in drinking and non-potable water using ab SCIEX Triple Quad 5500 LC/MS/MS System and are currently supporting projects coming out of NC due to contamination in the Cape Fear River.

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Posted : January 18, 2018 10:35 am
Simon Roberts
Member
Compound
Q1
Q3
RT
DP
CE
HFPO-DA (Quant)
329
185
3.5
-35
-32
HFPO-DA (Qual)
329
169
3.5
-35
-20
13C3-HFPO-DA
332
185
3.5
-35
-32
 
 
 
 
 
 

 

These parameters can be used for HFPO-DA and it's internal standard. This compound can be analyzed using the method shown in this application note:

Analysis of Hexafluoropropylene Oxide Dimer Acid (HFPO-DA), Commonly Known as Gen-X, and Related PFAS Compounds

This post was modified 1 year ago 2 times by
This post was modified 7 months ago by christie.hunter@sciex.com
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Posted : January 24, 2018 12:41 pm
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