GEN-MKT-18-7897-A
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While an in-depth discussion of method development and optimization for the Echo® MS system is beyond the scope of a community post, here are some points to consider as part of the process:
Recommended starting conditions
When optimizing a new compound or beginning method development for a new assay, it’s helpful to have a series of conditions that can be used as a starting point. Note that when developing a new assay for a new compound, it’s recommended to optimize the compound using a mostly aqueous standard first to generate the MRM(s) if they are not already known, and to then refine the acoustic ejection method, which includes selecting the carrier solvent and modifier.
Here, we share a few conditions to help you get started (keep in mind that while these conditions may not be optimal for your final method, they should produce peaks that can be further improved upon):
RUO-MKT-18-13648-A
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Nice, thanks .!
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