For all those interested in learning about all the cool applications possible with AEMS and the Echo MS system, here is a list of presentations at ASMS 2023. Monday: MOH 3:50pm – Intact protein analysis MP 294 – metabolite identification MP 312 Compound QC Tuesday TOB...
Technology
Find answers to your technology questions about SCIEX hardware and software solutions, to get the most out of your workflows. Learn from the experts and your peers.

General question on SCIEX 7500
Good morning.

Methods for OPI electrode cleaning for Echo® MS system electrodes
Depending on the samples you are running on the system, it is possible for the Open Port Interface (OPI) electrode to become dirty or occluded over time. Below are two different cleaning strategies that can help you maintain your Echo® MS system and keep your OPI...

Automation integration for the Echo® MS system
The Echo® MS system is specifically designed to be compatible with a variety of automation options to allow labs the flexibility to personalize their setup to meet their specific needs. To help you make the best decisions for your own lab, here are the answers to some...

Journal publications using the Echo® MS system
The Echo® MS system is a novel platform for Acoustic Ejection Mass Spectrometry (AEMS) and combines the speed of acoustic sampling with the selectivity of mass spectrometry. This platform has been designed for high throughput analysis of small molecules, metabolites,...

Please increase the number of files saved as the dispensing log
We found the dispensing log in the folder at C:\ProgramData\SCIEX\EchoMS\Data.

Assess the performance of the Echo® MS system
To obtain the best, most reproducible results using the Echo MS system, it is important to select the best solvent for your analyte and matrix and to ensure the flow rate is optimized for your solvent. Please review this flow rate optimization community post to...

Back to the new basics: Part 3 | LC vs. LC-MS and what it means for your lab
In this final installment of our “Back to the new basics” series, we take one more look at analytical techniques and best practices in the lab, and opportunities to improve efficiency. Here, we explore the basic principles of high-performance liquid chromatography (LC) and liquid chromatography mass spectrometry (LC-MS), and how these techniques can affect a lab’s efficiency and productivity.

Back to the new basics: Part 2 | Do I need a single quadrupole or a triple quadrupole system?
In this second installment of our 3-part “Back to the new basics” series, we continue to look at ways to improve lab productivity by using efficient techniques. The number of instrument options out there can be mind-boggling. Finding the right instrument—one that offers varying degrees of sensitivity, selectivity and specificity to meet your analytical needs—can be an intimidating challenge.

How to optimize sample plating to run Echo MS system in ‘Fast acquisition mode’
The Echo MS system can acquire data extremely rapidly, at 1 second per sample. To achieve this speed, it should be ensured that there is adequate time between ejections for the analyte signal to return to baseline between ejections. Plating your samples such that you...