I just wanted to thank the readers here, both the OneOmics suite users who’ve shared their time and watched OneOmics grow, and for all the talented developers and scientists who’ve made OneOmics suite what it is today.

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by April Quinn-Paquet | Sep 22, 2022 | Bioanalysis/PK, Biopharma, Genomics, Life Science Research, Lipidomics, Metabolomics, Multi-Omics, OneOmics, Pharma, Proteomics, SCIEX information, Software
I just wanted to thank the readers here, both the OneOmics suite users who’ve shared their time and watched OneOmics grow, and for all the talented developers and scientists who’ve made OneOmics suite what it is today.
by Christie Hunter | Jul 6, 2022 | Life Science Research, Lipidomics, Methods / workflows, QTRAP / Triple Quad, SCIEX information
Lipidomics Quantification of lipids in complex biological samples is challenging and often requires a detailed knowledge of lipids and lipid analysis methods. The inherent complexity of the lipidome means that identifying and quantifying different lipid classes and...
by Roz Jenkins | May 25, 2022 | Data processing, Life Science Research, ProteinPilot, Proteomics, QTOF, Questions
I have prepared a spectral library for a phosphopeptide enriched sample and I am generating my SWATH samples from similarly enriched samples. The problem is that when I use DIA-NN for the retention time alignment and quant, it doesn’t recognise the terminology of the spectral library annotated by ProteinPilot. DIA-NN recognises Unimod:21 for phosphorylation, but PP uses phospho(Tyr) etc. Other than changing the data dictionary to get around the mismatch, anyone have any suggestions for how I might resolve this? Thank you, Roz
by Christie Hunter | May 20, 2022 | Data processing, Life Science Research, Proteomics, SCIEX information, ZenoTOF
Below is a summary of various other software packages that are useful for processing proteomics data from the ZenoTOF 7600 system. Note this list is not comprehensive and only covers the tools we have lightly tested to date. Acquisition Type Software Files needed...
by Christie Hunter | May 9, 2022 | Data acquisition, Ion sources, Life Science Research, Proteomics, SCIEX information, ZenoTOF
This series of videos outlines how a user can easily switch sources and operate the system in different LC flow regimes.
by Christie Hunter | Apr 29, 2022 | Data processing, Life Science Research, Proteomics, SCIEX information, ZenoTOF
While generating proteomic spectral libraries today is relatively easy, sometimes a library is needed and there is not time or need to generate a deep library using the traditional data-dependent acquisition approach. Here, a strategy will be outlined to generate a...
by Christie Hunter | Apr 29, 2022 | Data processing, Life Science Research, Proteomics, SCIEX information, ZenoTOF
DIA-NN software is a powerful software tool for processing data independent acquisition (DIA) proteomics datasets. It uses neural networks and other algorithms to identify and quantify peptides and proteins from DIA data and is specifically optimized for fast...