Biopharma

Celebrating customer experience: Insights from SCIEX leaders

by Andrea Mueller | Oct 1, 2026 | Biopharma, Blogs, Clinical, Environmental / Industrial, Food / Beverage, Forensic, Life Science Research, Pharma, Technology

Customer Experience Day (CX Day) is a special occasion for SCIEX, celebrated every first Tuesday in October. It’s a day dedicated to recognizing the incredible value of our customers and the relentless dedication of our associates who strive to make every interaction meaningful. At SCIEX, our commitment to customer experience is woven into the fabric of everything we do. From providing cutting-edge solutions to offering unwavering support, we aim to build lasting relationships and exceed expectations. Join us as we delve into the insights from our leaders on what customer experience means to SCIEX and how it shapes our journey.

Why traditional MS/MS falls short for ADCs and how electron-activated dissociation (EAD) changes the equation

by Roxana McCloskey | Sep 14, 2026 | Biopharma, Blogs

Antibody-drug conjugates (ADCs) are among the most promising—and analytically demanding—modalities in biopharma today. By combining large, heterogeneous antibodies with chemically labile payloads and linkers, ADCs introduce a level of structural complexity that challenges conventional analytical workflows. It also poses the challenge that the very features you need to measure are often the easiest to lose during analysis.

Six benefits of remote support every laboratory should know

by Andrea Mueller | Sep 14, 2026 | Biopharma, Blogs, Environmental / Industrial, Food / Beverage, Food and Beverage, Forensic, Instrument maintenance, Life Science Research, Optimizing Performance, Pharma, Service, Support, Technology, Training

Imagine having a tech expert at your fingertips to solve computer issues or a fitness trainer guiding you through workouts from the comfort of your home. In today’s fast-paced world, the ability to provide and receive service and support remotely is no longer a luxury but a necessity. Whether it’s troubleshooting a software issue, repairing a device, offering customer assistance, or enjoying the convenience of telehealth as a private individual, remote capabilities have revolutionized how businesses operate and how individuals get help

The costly consequences of unplanned downtime

by Andrew Wilcox | Sep 14, 2026 | Biopharma, Blogs, Clinical, Environmental / Industrial, Food / Beverage, Forensic, Life Science Research, Pharma, Technology

Unplanned downtime is a formidable adversary that businesses across various industries strive to minimize. Defined as the unexpected interruption of regular operations, unplanned downtime can wreak havoc on productivity, profitability and customer satisfaction. In this article, we delve into the causes of unplanned downtime, its far-reaching consequences and strategies to mitigate its impact.

Managing ADC characterization: The challenge of turning complexity into confidence

by Roxana McCloskey | Aug 25, 2026 | Biopharma, Blogs

Unlike traditional monoclonal antibodies, ADCs combine an antibody backbone with linker chemistry and a cytotoxic payload. This multi-component architecture introduces overlapping layers of heterogeneity, including drug-to-antibody ratio (DAR) distributions, charge variants, post-translational modifications, and structural changes at both the intact and subunit levels. Across ADC development, these characteristics are considered critical quality attributes that must be characterized, understood, and monitored.

ADC analytics FAQs: Answering the most common questions about ADC characterization

by Roxana McCloskey | Aug 14, 2026 | Biopharma, Blogs

Antibody-drug conjugates (ADCs) have emerged as one of the fastest-growing classes of biotherapeutics, combining the targeting specificity of monoclonal antibodies with the potency of cytotoxic payloads. However, this unique architecture also introduces significant analytical complexity. From drug-to-antibody ratio (DAR) distributions and charge variants to conjugation sites and structural modifications, ADCs present multiple, interconnected sources of heterogeneity that must be understood to ensure product quality and performance.

Bioanalysis across modalities: Advancing confident decisions with modern LC‑MS strategies

by SCIEX Community | Jul 22, 2026 | Biopharma, Blogs, Pharma

As therapeutic pipelines continue to diversify, bioanalysis is being asked to do more than ever before. From small molecules to complex biologics, today’s scientists must generate high‑quality, reliable data across a growing range of molecule types and workflows, often under increasing time pressure.

Confident glycan characterization with EAD‑enabled LC‑MS workflows

by Roxana McCloskey | Jun 30, 2026 | Biopharma, Blogs

Glycosylation is one of the more structurally diverse and biologically impactful PTMs in protein therapeutics. Both N‑linked and O‑linked glycans influence protein folding, stability, and biological activity. Given these effects on biotherapeutics, glycosylation is a closely monitored critical quality attribute (CQA). Comprehensive and site‑specific characterization of glycosylation is essential for informed decision‑making throughout drug discovery and development.

Why capillary electrophoresis still matters in modern biopharma

by Roxana McCloskey | Jun 9, 2026 | Biopharma, Blogs, CE

Explore why capillary electrophoresis remains essential for high resolution, confident analytics across modern biopharma modalities, from proteins to mRNA and gene therapies

Where does capillary electrophoresis fit across drug development?

by Roxana McCloskey | Jun 9, 2026 | Biopharma, Blogs, CE

Capillary electrophoresis (CE) is not confined to a single point in the drug development lifecycle. Its value comes from the ability to deliver high‑resolution, reproducible separations that remain relevant as analytical questions evolve, from early discovery through late‑stage development and lot release.

Biologics characterization pose many challenges due to the diversity of the biomolecules. Learn about the many powerful tools that allow researchers to fully characterize and quantify their biologic drugs, using mass spectrometry and capillary electrophoresis instrumentation.

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