QTRAP / Triple Quad

PFAS FAQ’s: Ask our experts

by Gitte Barknowitz | Jan 23, 2026 | Blogs, Environmental / Industrial, Food / Beverage, QTRAP / Triple Quad

PFAS analysis is complex, but expert guidance doesn’t have to be. In this episode of our ‘Ask the PFAS expert series’, we’re joined by Michael Scherer, Application Lead for Food and Environmental, to answer the most pressing questions in PFAS analysis. From why LC-MS/MS systems are the gold standard for analyzing diverse PFAS compounds, to which EU methods deliver reliable results for drinking water, and to practical steps to prevent contamination, Michael shares actionable insights to help laboratories achieve accuracy, consistency, and confidence in their workflows.

Choosing the right LC-MS system for bioanalysis: Let’s make it easier

by Kirsten Craven | Dec 23, 2025 | Blogs, Pharma, QTRAP / Triple Quad

Investing in a new liquid chromatography-mass spectrometry (LC-MS) system is a big decision, especially when your lab handles a wide variety of analytical tasks. With so many options out there, it’s easy to feel overwhelmed.

Q/A: Quantitative and qualitative solutions for large-panel pesticides assays using SCIEX Triple Quad and QTRAP systems

by Holly Lee | Jul 24, 2025 | Blogs, Food / Beverage, QTRAP / Triple Quad

In a recent webinar, which is now available on-demand, Holly Lee powerful strategies to tackle complex residue testing. From boosting throughput to fine-tuning method sensitivity, Holly shared key ways to maximize performance across large pesticide panels.

A toast to summer… and a side of trifluoroacetic acid?

by Gitte Barknowitz | Jul 17, 2025 | Blogs, Environmental / Industrial, QTRAP / Triple Quad, SCIEX OS software

Whether we are raising glasses of rosé in a vineyard in France or enjoying a lager in a casual street restaurant in China, it is likely that the last thing on many people’s minds is the chemical risks from their beverage. Unless you work in food science, then it might actually be the first thing.

Selecting an LC-MS system for quantitation of pharmaceutical drug development

by Kirsten Craven | Oct 29, 2024 | Blogs, Echo® MS+ system, Pharma, QTRAP / Triple Quad, ZenoTOF 7600 system

We understand you are busy, needing to prioritize running instruments, reporting results and managing your laboratory to meet deadlines. We created a solution guide to explain how SCIEX systems fit in the drug development pipeline to save you time evaluating options.

Nitrosamines: Where are we now?

by SCIEX Community | Oct 10, 2024 | Blogs, Pharma, QTRAP / Triple Quad

Nitrosamines are a large group of N-nitroso compounds that share a common functional N-N=O group. They are produced by a chemical reaction between a nitrosating agent and a secondary or tertiary amine. Back in 2018, nitrosamines suddenly found themselves in the spotlight when they were unexpectedly detected in medications for high blood pressure. Since then, they have been found in several other prescription medications, including those for heartburn, acid reflux and diabetes, resulting in manufacturers recalling some common medications.

PFAS analysis in food: a robustness study in sensitivity and stability

by Holly Lee | Sep 27, 2024 | Blogs, Environmental / Industrial, Food / Beverage, QTRAP / Triple Quad

The combination of per- and polyfluoroalkyl substances (PFAS) testing, trace-level regulatory requirements and complex MS applications can be intimidating. In a recent webinar, now available on demand, SCIEX PFAS expert Craig Butt demonstrated how the new SCIEX 7500+ system can help make PFAS testing easier.

LC-MS system replacement: Are you ready?

by Kirsten Craven | Aug 16, 2024 | Blogs, Pharma, QTRAP / Triple Quad

Meeting deadlines in a bioanalysis laboratory can be a big challenge. Older, less sensitive and less reliable LC-MS systems make it even more difficult. Even the disruption caused by the installation and validation can be disconcerting and delay decisions. Does this sound familiar?

A 2-fold revolution: MS approaches for the bioanalysis of oligonucleotide therapeutics

by Kerstin Pohl | Apr 29, 2024 | Biopharma, Blogs, Pharma, QTOF, QTRAP / Triple Quad, ZenoTOF 7600 system

In 1998, the US Food and Drug Administration (FDA) approved fomivirsen as the first therapeutic oligonucleotide therapeutic. This approval marked a revolution of mechanism of action discovered decades before finally coming to fruition. Since then, the landscape of chemical modifications of oligonucleotides, conjugations and formulations has evolved tremendously, contributing to improvements in stability, efficacy and safety. Today, more than a dozen antisense oligonucleotides (ASOs) and small interfering RNA (siRNA) drugs are on the market, most of which are designated as orphan drugs for treating rare genetic diseases.

Unlock the benefits of nominal mass spectrometry for NPS analysis

by Pierre Negri | Mar 11, 2024 | Blogs, Clinical, Forensic, QTRAP / Triple Quad, Toxicology

The development of analytical methods for the detection and quantitation of drugs and metabolites in a range of biological matrices is a challenging process. Forensic toxicology labs need a reproducible and reliable methodology to ensure the robustness of the data and the quality of the results. They also need robust and sensitive instrumentation that can detect drugs at trace levels with high specificity, especially when it comes to novel psychoactive substances (NPS), which can be difficult to monitor and control.