QTRAP / Triple Quad

QTRAP / Triple Quad systems

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Using Scheduled Ionization to reduce system ion load for proteomics data acquisition

Using Scheduled Ionization to reduce system ion load for proteomics data acquisition

When analyzing highly complex samples from biological matrices, there can be significant amounts of material that elute in the wash cycle of the LC run, depending on the up-front sample preparation used.  The Scheduled Ionization mode, available in both SCIEX OS...

Back to the new basics: Part 3 | LC vs. LC-MS and what it means for your lab

Back to the new basics: Part 3 | LC vs. LC-MS and what it means for your lab

In this final installment of our “Back to the new basics” series, we take one more look at analytical techniques and best practices in the lab, and opportunities to improve efficiency. Here, we explore the basic principles of high-performance liquid chromatography (LC) and liquid chromatography mass spectrometry (LC-MS), and how these techniques can affect a lab’s efficiency and productivity.

Back to the new basics: Part 2 | Do I need a single quadrupole or a triple quadrupole system?

Back to the new basics: Part 2 | Do I need a single quadrupole or a triple quadrupole system?

In this second installment of our 3-part “Back to the new basics” series, we continue to look at ways to improve lab productivity by using efficient techniques. The number of instrument options out there can be mind-boggling. Finding the right instrument—one that offers varying degrees of sensitivity, selectivity and specificity to meet your analytical needs—can be an intimidating challenge.

sMRM Pro Builder template tutorial

sMRM Pro Builder template tutorial

The sMRM Pro Builder template is an Excel-based tool that can help you implement large panels of analytes in your lab. The Excel sheet will take your preliminary experimental results and compute retention times, retention time window widths and dwell time weighting to optimize your targeted assay.

MRM method transfer from a SCIEX Triple Quad or QTRAP 6500+ system to the SCIEX 7500 system

MRM method transfer from a SCIEX Triple Quad or QTRAP 6500+ system to the SCIEX 7500 system

General recommendations when beginning method development Objective: The purpose of this document is to provide a quick reference for transferring MRM-based quantification methods from a SCIEX Triple Quad or QTRAP 6500+ system to a SCIEX 7500 system. While the best...