![Country [Change]](http://images.sciex.com/shared/icons/globe-white.png){kind=icon}
Country [Change]
Shop
Partners
AB Sciex is doing business as SCIEX. © 2010-2018 AB Sciex. The trademarks mentioned herein are the property of the AB Sciex Pte. Ltd. or their respective owners. AB SCIEX™ is being used under license. Beckman Coulter® is being used under license. Product(s) may not be available in all countries. For information on availability, please contact your local representative. For research use only. Not for use in diagnostic procedures.
Read time: 7 minutes Prime editing (PE) is a next-generation gene editing technology that utilizes a Cas9 protein fused to a prime editing guide ribonucleic acid (pegRNA) to achieve high CRISPR/Cas9 editing efficiency and precision. However, the length requirement of...
Read time: 6 minutes Certain next-gen vaccines and gene therapy applications rely on the usage of adeno-associated viruses (AAV) as a delivery vehicle. To ensure the safety and efficacy of viral vector drugs, multiple critical quality attributes (CQAs) need to be well...
Read Time: 7 minutes Interviewee: Jane Luo (PhD), Senior Scientist, SCIEX Lipid nanoparticles (LNPs) are widely used vehicles for mRNA-based therapeutics and vaccines. However, ionizable lipids used in LNPs can be susceptible to N-oxide impurities that can cause...
Read Time: 9 minutes Lipid nanoparticles (LNPs) are widely used vehicles for messenger RNA (mRNA)-based therapeutics and vaccines. However, ionizable lipids used in LNPs can be susceptible to N-oxide impurities that can cause functional loss of the mRNA cargo. In a...
Read time: 9 minutes Currently, there are 3 main types of in vitro transcribed (IVT) RNA drugs, encapsulated in lipid nanoparticles (LNPs). Two of these—conventional messenger RNA (mRNA) and base-modified mRNA (bmRNA), which incorporates chemically modified...
Read time: 8 minutes Lipid-based nanoparticles (LNPs) are effective non-viral vectors for delivering messenger RNA (mRNA) products or other drug substances. In a recent webinar, Jérémie Parot (PhD), Research Scientist at SINTEF Industry, demonstrated the robust and...
Contact Support