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Apr 13, 2021 | Blogs, Environmental / Industrial | 0 comments
Read time: 4 minutes
Introduction to cannabis: analysis
Cannabis is a broad umbrella of classification that includes both hemp and marijuana. Check out a recent blog that lays out the definitions. This blog will focus on the common criteria we look at when conducting cannabis testing, including potency, pesticides and mycotoxins.
Potency: how do you test for it?
Based on individual state regulatory requirements in the US, the potency of commercial cannabis products must be reported. The percentage of THC is printed on cannabis product labels after being certified by a licensed cannabis testing facility. The methodology for obtaining cannabis potency values can vary based on the analytical technique and instrumentation used, which gives testing facilities options for customizing or streamlining their workflows. While marijuana potency testing can vary, hemp analysis has to be accurate, or the crop is considered cannabis and subject to federal confiscation and fines. The US, however, lacks standardized methods to assess products for potency and safety. That’s a big problem for the labs that are tasked with doing the testing. There have been many challenges in the uniformity of potency results across testing sites. Some manufacturers will go to the lab that gives them the highest potency results. Pesticides, mycotoxins and terpenes, oh my!
As states in the US struggle to set standards for testing, both consumers and retailers are becoming increasingly discerning. Because of the variability and diversity of the matrix composition of samples—which can include cannabinoids, terpenes, sugars, fatty acids and more—analyzing cannabis and hemp for pesticides can be daunting. This is especially true for high-throughput cannabis and hemp residue testing. If you want to learn more about this topic, check out our tips and tricks for pesticide residue analysis in cannabis. Stay tuned for more blogs and information on the analysis of cannabis and hemp.
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In monoclonal antibody (mAb) development, assessment of purity and integrity of the protein in question is critical. CE‑SDS is the gold standard assay and is routinely run from analytical development through QC and lot release. It’s trusted because it consistently delivers quantitative, size‑based insight into purity and fragmentation, and it fits naturally into regulated environments.
In drug discovery and development, Metabolite Identification (Met ID) plays a critical role in understanding biotransformation pathways, ensuring safety, and meeting regulatory requirements. Advanced mass spectrometry techniques have revolutionized this process, particularly through electron-based fragmentation methods such as Electron Activated Dissociation (EAD) and Electron Transfer Dissociation (ETD). While both techniques leverage electron interactions to generate informative fragment ions, they differ significantly in mechanism, performance, and suitability for Met ID workflows.
In analytical laboratories, performance is not optional. Whether supporting regulated pharmaceutical workflows, high-throughput CRO operations, clinical reporting, or food and environmental testing, your mass spectrometry and capillary electrophoresis systems are critical to productivity, compliance, and scientific confidence.
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