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Gregg Czerwieniec

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March 7, 2024
High mass tuning calibration for ZenoTOF 7600

Hi,

 

I have a question regarding the default used in the autotune for the ZenoTOF 7600. The tune and calibrant tops out at a max of 849Da or something like that. When looking at antibodies the charge envelope is way beyond this range, like 1800-3000 m/z.

 

For users that are looking out at this m/z range it would be nice if there was a calibrant as well as a tune for resolution, and sensitivity that encompassed the range we are working in. I know other vendors used Caesium Iodide for high mass range. Is there a way to use something similar as a custom tune mix?

 

 

Thanks,

 

Gregg

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