Take on New Analytical Challenges with the TripleTOF 6600 Accurate Mass System

Aug 25, 2017 | Blogs, Technology | 0 comments

Stay ahead of the curve by using the most advanced and versatile high-resolution accurate mass technology. The TripleTOF® 6600 accurate mass QTOF system can help you to analyze your samples faster, without compromising between speed, resolution, and sensitivity. Explore the technological advances that give this system the performance edge.

  1. Produce More Ions:  IonDrive™ Turbo V Source increases ion production by using enhanced gas flow dynamics and optimized heater configuration
  2. Capture More Ions: Qjet® Ion Guide provides large capture radius for efficient transfer of ions from source to quadrupole optics
  3. Focus More Ions: LINAC® collision cell provides high resolution through improved ion focusing, along with efficient and rapid ion transmission to  eliminate cross-talk and high duty cycle for maximum sensitivity
  4. Detect More Ions: Get 5-orders of linear dynamic range with the 4-channel MCP detector with ADC processing, which operates at low bias voltage to improve robustness and lifetime
  5. Resolve More Ions: Time-of-flight analyzer uses a 2-stage mirror and 15 kV acceleration to improve resolution and efficiency

In addition, you can get the flexibility your lab needs by configuring with nanoflow, microflow, conventional flow LC, or with capillary electrophoresis spray ionization (CESI) separation systems. And condensed data file sizes simplify and streamlines data storage and portability, without losses in data quality, completeness, or security.

ADC analytics FAQs: Answering the most common questions about ADC characterization

Antibody-drug conjugates (ADCs) have emerged as one of the fastest-growing classes of biotherapeutics, combining the targeting specificity of monoclonal antibodies with the potency of cytotoxic payloads. However, this unique architecture also introduces significant analytical complexity. From drug-to-antibody ratio (DAR) distributions and charge variants to conjugation sites and structural modifications, ADCs present multiple, interconnected sources of heterogeneity that must be understood to ensure product quality and performance.

Sterile but toxic: Cereulide detection in food matrices

In a recent webinar, Ming Gao, Ph.D., Senior Research Chemist at Mérieux NutriSciences, explored the growing challenge of cereulide contamination in food products and the analytical strategies needed to detect this heat-stable toxin at trace levels. The session examined how LC-MS/MS can help laboratories overcome the limitations of traditional microbiological screening and meet emerging regulatory requirements.

How SCIEX Now empowers mass spec users to work with more control, clarity and confidence

In this interview, Andy Wilcox, Senior Market Development Manager, Aftermarket and Software, speaks with Susanna Baqué, Senior Director of Global Customer Experience, about how SCIEX Now gives customers one connected digital workspace to manage instruments, reduce time spent searching for information, resolve issues faster and keep their laboratory running more efficiently and with greater confidence.

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