Technical notes using the Echo® MS+ system

Jun 17, 2025 | Blogs, Echo® MS+ system, Pharma | 0 comments

The Echo® MS+ system comprises of an open-port interface (OPI) and acoustic droplet ejection (ADE) module which could be coupled with a mass spectrometer. The mass spectrometer could either be a SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system. This non-liquid chromatography based; high-throughput screening platform enables rapid analysis of compounds at speeds of up to 1 sample/second.

Download the technical notes below to learn more about this game-changing technology and the applications that can be conducted using the Echo® MS+ system.

Rapid MS/MS analysis with Acoustic Ejection Mass Spectrometry (AEMS). SCIEX technical note, RUO-MKT-02-11385-A
True high throughput bioanalysis using the Echo® MS System. SCIEX technical note, RUO-MKT-02-11649-A
Rapid quantitative analysis of fermentation broth samples to assess efficiency of engineered yeast strain turnover. SCIEX technical note, RUO-MKT-02-11695-A
Accelerating synthetic biology with very fast screening of metabolites in fermentation broth. SCIEX technical note, RUO-MKT-02-14011-A
Accelerated pharmacokinetic profiling and metabolite monitoring Using Echo® MS System. SCIEX technical note, RUO-MKT-02-12894-A
True high-throughput analysis of transporter activity screens. SCIEX technical note, RUO-MKT-02-13968-A
Ultra-fast quantification of alprazolam in human plasma extracts. SCIEX technical note, RUO-MKT-02-13059-A
High-throughput metabolite quantification for synthetic biology. SCIEX technical note, RUO-MKT-02-13362-A
Ultra-fast, accurate and simultaneous quantification of ritonavir and lopinavir in human plasma. SCIEX technical note, RUO-MKT-02-13058-A
Accelerating turnaround time in high-throughput ADME pipelines. SCIEX technical note, RUO-MKT-02-14235-B
Automating high-throughput ADME assays with LeadScape® 3.0 Analyze software on the Echo® MS system. SCIEX technical note, RUO-MKT-02-14841-A
Optimizing robustness for high-throughput screening on the Echo® MS+ system. SCIEX technical note, MKT- 31348-A
High-speed compound quality assessment using Acoustic Ejection Mass Spectrometry. SCIEX technical note, MKT-31143-A
High-throughput protein analysis using acoustic ejection mass spectrometry. SCIEX technical note, MKT- 31206-A
An automated, real-time measurement of kinetic hydrolysis of glucuronide using the Echo® MS+ system with ZenoTOF 7600 system. SCIEX technical note, MKT-31227-A
Automated, rapid method optimization and buffer screening using the Echo® MS+ system with ZenoTOF 7600 system. SCIEX technical note, MKT-30777-1
Determining optimal buffer concentration and compatibility for high-throughput intact protein analysis. SCIEX technical note, MKT-30944-A
High-resolution, specific analysis of arginine and citrulline on the Echo® MS+ system with ZenoTOF 7600 system. SCIEX technical note, MKT-27824-A
Rapid insulin analysis before-and-after TCEP reduction using the Echo® MS+ system with ZenoTOF 7600 system. SCIEX technical note, MKT-27824-A
Rapid and accurate quantitation of thyroglobulin biomarkers using the Echo® MS+ system with ZenoTOF 7600 system. SCIEX technical note, MKT-27824-A

Q/A: Quantitative and qualitative solutions for large-panel pesticides assays using SCIEX Triple Quad and QTRAP systems

In a recent webinar, which is now available on-demand, Holly Lee powerful strategies to tackle complex residue testing. From boosting throughput to fine-tuning method sensitivity, Holly shared key ways to maximize performance across large pesticide panels.

A toast to summer… and a side of trifluoroacetic acid?

Whether we are raising glasses of rosé in a vineyard in France or enjoying a lager in a casual street restaurant in China, it is likely that the last thing on many people’s minds is the chemical risks from their beverage. Unless you work in food science, then it might actually be the first thing.

The economics of PFAS testing: A strategic perspective for laboratory managers

As PFAS regulations tighten globally, laboratory managers are navigating a complex economic landscape. Whether operating in a commercial or non- commercial setting, the pressure to deliver accurate, defensible, and timely PFAS data is mounting. At SCIEX we understand that the right technology can turn this regulatory challenge into a strategic opportunity.

Posted by

Anuja Bhalkikar

Anuja Bhalkikar is a Senior Scientist at SCIEX’s Echo® MS Center of Excellence. She supports the Echo® MS+ product line and is responsible for conducting customer demonstrations, providing technical support to clients that includes streamlining automation along with the EchoMS+ system, and generating new workflows. Anuja earned her Ph.D. in Chemistry from the University of Nebraska-Lincoln. She worked in a precision oncology clinical testing laboratory and the bioanalysis division at PPD a part of Thermo Fisher Scientific before joining SCIEX.

0 Comments