GEN-MKT-18-7897-A
Apr 23, 2026 | Blogs, Service, Support, Training | 0 comments
Read time: 3 minutes
In today’s fast-paced analytical laboratories, uptime is not just important; it is mission-critical. Whether you are running high-throughput bioanalysis, environmental testing, or pharmaceutical workflows, every minute of LC-MS downtime can impact productivity, data quality, and timelines.
That is why we are excited to introduce a smarter and faster way to troubleshoot.
Troubleshoot LC-MS like a pro
We are proud to launch the interactive LC-MS troubleshooting guide for SCIEX Triple Quad™ and QTRAP systems, which is now available on the SCIEX Now learning hub.
Built with direct input from our global customer community, this free, on-demand resource is designed to help you quickly diagnose and resolve common instrument challenges, without waiting for service intervention.
At SCIEX, our philosophy is simple: Customers talk, we listen. This guide is a direct reflection of that commitment.
Why this guide matters
Troubleshooting LC-MS systems can often feel complex and time-consuming. Traditional approaches may involve:
This interactive guide changes that. By enabling self-guided troubleshooting, you can:
Designed for real-world lab challenges
The guide focuses specifically on the most common issues encountered with Triple Quad and QTRAP LC-MS systems, based on real customer experiences and service data.
Rather than static documentation, it delivers a dynamic, decision-tree experience:
This structured approach ensures you are not just guessing but systematically narrowing down the root cause.
Key features at a glance
Practical troubleshooting tips for LC-MS users
While the guide provides in-depth support, here are a few best practices every LC-MS user can apply:
These habits, combined with the interactive guide, can significantly reduce disruption to your workflows.
Access the guide today
You can access the interactive LC-MS Troubleshooting guide directly on the SCIEX Now learning hub.
We encourage you to explore the guide, bookmark it for future use, and share it with your team.
You don´t have an account with SCIEX yet? Register to unlock the power of SCIEX Now for your laboratory and access the learning hub.
Bonus tip: Watch our LC-MS/MS webinar series, “Maintenance and troubleshooting,” presented by Karl Oetjen, Senior Scientist for Technical Marketing and one of our resident PFAS experts at SCIEX, who helps you understand how to keep your system in tip-top shape and shows you a lot of tips and tricks to do so.
Supporting your success, every step of the way
This launch is part of our broader commitment to empowering laboratories with the tools, knowledge, and resources needed to succeed – independently and efficiently.
We are excited to hear your feedback as you begin using the guide, and we will continue evolving our resources based on your needs.
When your instruments perform at their best, so can you.
In biopharmaceutical development, sequence variants (SV) are considered an inherent risk of producing complex proteins in living systems. Sequence variants are unintended changes to the amino acid sequence of a biotherapeutic and can be caused by errors in transcription or translation in the host cell, or cell culture and process conditions. Detailed analysis of SVs is important in process and product development to ensure the drug’s safety and efficacy. Even low‑level sequence variants can have significant implications for product quality, safety, and efficacy, making their accurate detection and characterization a critical requirement across development, process optimization, and regulatory submission.
CE‑SDS remains a cornerstone assay for characterizing fragmentation, aggregation, and product‑related impurities in therapeutic proteins. UV detection has been the long‑standing standard. However, it frequently struggles with baseline noise, limited sensitivity for minor fragments, and subjective integration.
At SCIEX, innovation doesn’t stop at instruments; it extends to how you interact with your LC-MS/MS or CE systems every day. That’s why we’re excited to introduce the SCIEX Now spring 2026 improvements: a set of meaningful enhancements shaped directly by your feedback.
Posted by
You must be logged in to post a comment.
Share this post with your network