GEN-MKT-18-7897-A
Oct 13, 2020 | Biopharma, Blogs, Echo® MS+ system, Pharma | 0 comments
Imagine the productivity gains your lab could achieve with a technology that not only analyzes samples up to 50x faster than conventional quantitative LC-MS, but also eliminates tedious sample preparation, time-consuming LC method development and chromatographic run times.
Sound impossible? Not anymore.
Enter the new, exciting and very real Echo® MS System with:
Wait…no LC?
With its Acoustic Droplet Ejection (ADE) and Open Port Interface (OPI), the Echo MS System replaces conventional LC with game-changing technology that dramatically reduces the amount of time required for quantitative MS analysis. With no LC requirements, the Echo® MS System eliminates the need to spend time and effort developing separation methods. Troubleshooting LC problems and waiting for LC columns to wash, equilibrate and elute analytes disappear, all while delivering a speed of analysis that sets records for quantitative MS.
Imagine a 384 well plate finished in less than 7 minutes.1 With that kind of speed, entire discovery libraries containing millions of compounds can be quantitatively analyzed in a matter of days. Lead compounds are discovered faster, and project timelines can be radically accelerated.
Having this kind of speed means:
“Recently we heard comments from one of our collaborators. They are already starting to see the paradigm shift in their company. A lot of assays routinely run on the optical-based analytical instrument are now shifting to the mass-spec-based platform.”2Chang Liu, SCIEX R&D
With the Echo MS System, a fundamentally fast platform is combined with an effort-easing workflow that is more than the sum of its parts. With the capability to accelerate project turnaround times from months to weeks, days or even hours or minutes, the Echo MS System can dramatically improve your lab productivity.
To learn more about how you can massively scale up your productivity and RUN FAST, visit the Echo® MS System website for more information.
This blog is part 2 of a 3-part series on the Echo MS System. Read part 1 (How fast is fast? The Echo® MS System sets the record.), and part 3 (Scale it up! The Echo® MS System delivers unprecedented levels of productivity.).
References:
RUO-MKT-18-12283-A Echo® and Echo® MS are trademarks or registered trademarks of Labcyte Inc. in the United States and other countries, being used under license by SCIEX.
The Echo® MS+ system is a novel platform for Acoustic Ejection Mass Spectrometry (AEMS) and combines the speed of acoustic sampling with the selectivity of mass spectrometry. This platform has been designed for high throughput analysis of small and large molecules. The technology combines Acoustic Droplet Ejection (ADE), an Open Port Interface (OPI) and could be coupled with the SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system.
The Echo® MS+ system comprises of an open-port interface (OPI) and acoustic droplet ejection (ADE) module which could be coupled with a mass spectrometer. The mass spectrometer could either be a SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system. This non-liquid chromatography based; high-throughput screening platform enables rapid analysis of compounds at speeds of up to 1 sample/second.
The ability to consistently achieve reproducible results on many complex samples across multiple days is critical to a routine clinical laboratory. Laboratories relying on analytical instrumentation require stability and robustness to perform a variety of screening and confirmatory assays with confidence. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the preferred analytical method in the clinical laboratory to reliably perform clinical testing as it provides best-in-class performance and reliability for the most challenging assays. LC-MS/MS offers the required levels of sensitivity and specificity for the detection and quantitation of molecules from complex biological samples, helping laboratories deliver highly accurate data for a variety of clinically relevant analytes across a wide range of assays.
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