GEN-MKT-18-7897-A
Jun 3, 2016 | Blogs, Forensic | 0 comments
The importance of protecting a country’s border is a very topical issue. The war on drugs and terror is a 24/7 task 366 days a year (2016 is a leap year). The government agencies in charge must be vigilant and maintain instrumentation to prevent terrorism, drug trafficking, and other illegal activities. Mass Spectrometry is rapidly becoming the instrument of choice for border agencies throughout the world when it comes to explosive trace detection and forensic drug compounds.
In a recent paper in the Journal of Forensic Science1, a comprehensive evaluation using Mass Spectrometry for the trace detection of 2,4,6-trinitrotoluene, C-4, Semtex-H, Datasheet, and HMTD was conducted.
The technology employed in this study was a SCIEX API 3200™ System Mass Spectrometer coupled with the Scentinel system, a thermal desorption and atmospheric pressure chemical ionization (APCI) source, engineered by the trace forensic analysis experts at Mass Spec Analytical based in Bristol, United Kingdom. The unique feature of this technique is that it is a chromatography-free analytical solution. There is no need for intensive sample prep or LC gradient. The sample is introduced to the source and produces a response in a very short period. The findings of this evaluation concluded that,“The direct analysis by mass spectrometry using the Scentinel transformed the traditional day-long quantification analysis of solvent extraction chromatography to minutes, eliminated sample loss, and allowed the transfer efficiency to be quantified for every test surface used.”
The Canadian Border Service Agency (CBSA) requirement for testing explosives detectors is just one such application that could be carried out using this configuration. For more information on the forensic drug screening visit SCIEX.com and discover more about the forensic drug screening services from Mass Spec Analytical.
The latest solution for forensic analyte testing from SCIEX is the X500R QTOF System, an instrument that has been specifically engineered based on the requirements of forensic scientists throughout the world. To accompany the SCIEX OS software we have produced a comprehensive acquired High-Resolution Mass Spec Library, click here for more information about a free trial and XIC list.
1.Tam, M.; Pilon, P. and Zaknoun, H. of the Canadian Border Services Agency (CBSA) entitled “Quantified explosives transfer on surfaces for the evaluation of trace detection equipment”
For research use only. Not for use in diagnostic procedures.
The Echo® MS+ system is a novel platform for Acoustic Ejection Mass Spectrometry (AEMS) and combines the speed of acoustic sampling with the selectivity of mass spectrometry. This platform has been designed for high throughput analysis of small and large molecules. The technology combines Acoustic Droplet Ejection (ADE), an Open Port Interface (OPI) and could be coupled with the SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system.
The Echo® MS+ system comprises of an open-port interface (OPI) and acoustic droplet ejection (ADE) module which could be coupled with a mass spectrometer. The mass spectrometer could either be a SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system. This non-liquid chromatography based; high-throughput screening platform enables rapid analysis of compounds at speeds of up to 1 sample/second.
The ability to consistently achieve reproducible results on many complex samples across multiple days is critical to a routine clinical laboratory. Laboratories relying on analytical instrumentation require stability and robustness to perform a variety of screening and confirmatory assays with confidence. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the preferred analytical method in the clinical laboratory to reliably perform clinical testing as it provides best-in-class performance and reliability for the most challenging assays. LC-MS/MS offers the required levels of sensitivity and specificity for the detection and quantitation of molecules from complex biological samples, helping laboratories deliver highly accurate data for a variety of clinically relevant analytes across a wide range of assays.
Posted by
You must be logged in to post a comment.
Share this post with your network