GEN-MKT-18-7897-A
Aug 10, 2016 | Blogs, Forensic | 0 comments
How do you know what you can’t see? This is the challenge many a lab faces as they relentlessly test for novel psychoactive substances (NPS) as unknown samples with an ever-changing ingredient list make discovery difficult work at best. There are many reasons for the complexities of which you can discover in this application note, “Accurate Mass Screening Workflows for the Analysis of Novel Psychoactive Substances.” However, the biggest of which is that non-targeted findings can turn up thousands of molecular features in a single sample. Sifting through the peaks is laborious, and many are normal besides.
Therefore, in this application note, our researchers took a comparative screening approach to NPS by testing urine samples against a control group using high resolution and accurate mass LC-MS/MS. The TripleTOF® system was then operated in IDA mode to acquire MS and MS/MS information simultaneously.Using this method reduced the compound list from thousands to just 10. Now that is a much more manageable sample size for which to analyze peak findings.
Application Note Overview:
Be confident in your NPS sample. Review the application note in its entirety.Download the Designer Forensic Drug Analysis Solution Kit >
Useful FAQ document to enable researchers to focus on their scientific discoveries and insights rather than the complexities of data management.
In today’s environment in which labs are under pressure to reduce operating costs, many will compare the cost of a service contract between third-party providers and the original equipment manufacturer (OEM). At first glance, going with a service contract from a third-party provider may seem like a smart financial move, but experience shows they can introduce risks that affect reliability and compliance.
We recently hosted a webinar focused on streamlining forensic toxicology workflows, featuring expert speakers Maria Sarkisian from the San Francisco Office of the Chief Medical Examiner (SFOCME) and Dr. Dick Paul Kloos from the Netherlands Forensic Institute (NFI). The webinar explored innovative LC-MS/MS strategies that help forensic labs improve efficiency. In this blog, we share highlights from the Q&A session, where our speakers addressed the audience’s questions and shared actionable insights for forensic laboratory professionals.
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