Craig Butt

The detection of acid herbicides and urons by large volume injection

Sep 26, 2016 | Blogs, Environmental / Industrial | 0 comments

Pre-treatment versus direct injection – that is the question posed in the application note, “The Detection of Acidic Herbicides and Phenyl Ureas by LC-MS/MS with Large Volume Injection and Automated Column Switching.” It’s just one of the dozens of articles you will find within the Environmental Compendium (pages 1 to 4, pesticides) now available for download.Download Compendium >

Here’s the thing with Pesticides. They are taking a hit for their toxic pervasiveness to wildlife and suspected hormone-disrupting qualities. A problem as they find their way into drinking water via agriculture runoff or rogue dumping. This is not just in happening in Europe but the world over. However, since this particular report focuses on the UK, here is some background information on the state of water testing within the region. According to a Eurostat Report, seven percent of groundwater stations have reported excessive levels of one or more pesticides. However, as this application note points out, detection improvements are correlating with lowered acceptable limits. Hence, the need for a testing method that removes both cost and time associated with solid phase extraction and/or liquid/liquid extraction traditionally used for GC-MS analysis.

To give you an idea of what you will find not only in this study but throughout the environmental compendium, we’ve outlined some key points. For instance, you will discover how river and groundwater samples were obtained, filtered and directly injected into the LC-MS/MS system. Researchers thus follow up with graphics and content about:

Column details
Mass spectrometry
Gradient profiles
Calibration figures
MRM transitions
Signal to noise (S/N) calculations

Real-life scenarios and enforcing safety is a theme for the environmental compendium, and this application note demonstrates its effectiveness as the method is sensitive enough to be applied to U.K. surveillance work.

Overcoming uncertainty in your PFAS analysis

Just like gum on the bottom of a shoe, the existence of per- and poly-fluorinated alkyl substances (PFAS) in our environment is a sticky one. If you’re in the field of environmental testing, then you’re all too familiar with the threat these substances have on public health. While we have learned a lot about them over the years, there is still much more to understand. With the right detection methods, we can gather the information we need to empower us to make informed decisions on reducing the risks they impose.

6 Signs it’s time for a new vendor

A lab’s success depends on many factors from instrument quality to efficient operations, including being partnered with the right vendor. A vendor is more than just a supplier. They should provide you with a high-level quality of support in maximizing the lifespan and performance of your systems, reducing downtime, enhancing ROI and more. How do you know if you’re partnered with the right one? Here are six signs it might be time to find someone new.

Plasmid manufacturing: Setting up your CGT programs for success

Plasmid DNA serves a variety of purposes, from critical starting material for proteins, mRNA, viral vectors, and drug substances. Below, Dr. Emma Bjorgum, the Vice President of Client Services of the DNA Business Unit at Aldevron and an expert in plasmid manufacturing, provided insights into the process and an outlook on the future.

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Craig Butt

Craig has worked in the mass spectrometry industry for over 20 years and has been with SCIEX since 2016. As a senior product application specialist, he works with customers to understand their targeted screening workflows and provide solutions using high-resolution accurate mass spectrometry technologies.

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