Glycosylation Analysis Designed for the (Protein) Masses by SCIEX Community | Nov 9, 2016 | Biopharma, BlogsA variety of post-translational modifications (PTMs) can impact a biotherapeutic protein’s mass, but none are as common as glycosylation.[1] Hence, the headline for a recent article in Genetic Engineering and Biotechnology News, “Post-Translational Icing on the...
The History of Isotopic Labels for Quantitative Proteomics by Subhasish.Purkayastha@sciex.com | Nov 7, 2016 | Blogs, Life Science Research, Proteomics Proteomics has become a vital tool for biological scientists performing research on the healthy and diseased states of living things. It involves the large scale and systematic analysis of all proteins within a given cell, tissue, or organism. Because proteins are...
Integration of Electrophoresis into a Single, “Plug-and-Spray” Device Offers a New Approach for Metabolomics Applications by Baljit Ubhi | Oct 25, 2016 | Blogs, Life Science Research, Metabolomics Teasing apart the metabolome: CESI-MS separation of small, anionic compoundsMetabolomics, an emerging field focused on the chemical processes central to cellular metabolism gives scientists a snapshot of the cellular metabolic state, or metabolome at a given time....
Struggling to Analyze Small Volume Samples with Conventional LC-MS? by SCIEX Community | Oct 25, 2016 | Blogs, TechnologyThe M3 MicroLC System is designed for scientists who are struggling to analyze small volume samples with conventional LC-MS and need to lower their limits of quantitation while maintaining throughput and robustness. When designing the M3 MicroLC System, we...
Legal and Illicit Drugs in Wastewater Detected and Confirmed with QTRAP Technology by SCIEX Community | Oct 12, 2016 | Blogs, Environmental / IndustrialWhat happens when you up the sensitivity and lower detection limits on influent and effluent sewage tests? For starters, low levels of illegal drugs in samples begin to emerge. This is what researchers discovered when they combined the power of LC-MS/MS with the...