SWATH Acquisition – Master of All Trades by SCIEX Community | Apr 19, 2017 | Blogs, Technology SWATH® Acquisition is an innovative strategy for acquiring data on a TripleTOF® mass spectrometer. In a previous blog, we learned how SWATH works. Now let’s learn what it can do for different applications: ProteomicsHost-Cell Protein Analysis of BiologicsMetabolite...
The Power Behind LC-MS for Quantifying mAb Therapeutics by SCIEX Community | Apr 19, 2017 | Biopharma, BlogsQuantitation of monoclonal antibodies (mAbs) in biological fluids is important during all stages of antibody drug development. First developed in the 1970s, therapeutic mAbs have both research and medicinal impact as they can be used for diagnosis and treatment of a...
Data Independent Acquisition Mass Spectrometry with the Power of SWATH by SCIEX Community | Apr 6, 2017 | Blogs, Life Science Research, Metabolomics, ProteomicsThere are many different methods in use today to acquire data on a mass spectrometer, but few have generated as much buzz in recent years as SWATH technology. First reported 5 years ago by Ruedi Aebersold and his group1, SWATH® Acquisition on...
Volumetric Absorptive Microsampling and the SCIEX 6500+: A Pre-Clinical Case Study for the Biotherapeutic Exenatide by SCIEX Community | Apr 3, 2017 | Biopharma, BlogsIn an effort to Replace, Refine, and Reduce the number of animals used for pre-clinical research, several microsampling strategies have been implemented which allow for the consolidation of satellite TK and main study groups. In addition to the ethical gains driven by...
Say Goodbye to MetID Headaches, Say Hello to Automated Large Molecule Catabolism Processing by Kelli Jonakin | Mar 29, 2017 | Biopharma, BlogsIs your mind swimming with large molecule catabolism data? Do you spend hours manually processing through complex spreadsheets to match your data with theoretical biologic catabolites? Are you wasting precious time by drawing out and processing your therapeutic...