GEN-MKT-18-7897-A
Jan 29, 2023 | Biopharma, Blogs, Echo MS, Pharma | 1 comment
You asked, we answered! With analysis speeds of at least 1 sample per second, the Echo® MS system has created a buzz in the industry. This is up to 50x faster than conventional LC-MS/MS. This revolutionary tool for drug discovery and development has led to many questions from scientists and researchers around the world. We answer the top 7 Echo® MS system questions here.
The sample ejection volume for the Echo® MS system is about 0.1% of what you are injecting into an LC-MS system. Therefore, you are putting many fewer contaminants into the system over the same period of time.
The SCIEX OS software controls the system. This allows us to automatically process the data and export the results to any visualization software or LIMS. The SCIEX OS API (Application Programming Interface) allows integration with automation software from robotics vendors.
What types of liquid handling systems can be interfaced upstream of the Echo MS system? And what plate/sample throughput rates are possible?
The system is compatible with any vendor’s robotics system that can manage 384- and 1536-well plates. The cycle time for 384-well plates is less than 10 minutes, and for 1536-well plates it is less than 30 minutes.
The total size of the system is approximately 1.3 meters x 1.4 meters. This does not include the acquisition computer (which can be located up to 2 meters from the system) or the 1 meter of service access required around the entire system.
For a 384-well plate, the minimum volume required in the well is 20 µL and for 1536-well plates the minimum volume required is 3 µL. This is to ensure efficient ejection of the sample droplet.
Do you have a question? Please submit your question today or add it below in the comments.
Learn more about what the Echo® MS system can do for your lab at sciex.com/echoms. You will be able to see inside the system, download the brochure, gain access to technical notes, watch the video and request a quote.
In a recent webinar, available on demand, scientists Luiza Chrojan and Ryan Hylands from Pharmaron, provided insights into the deployment of capillary gel electrophoresis (CGE) within cell and gene therapy. Luiza and Ryan shared purity data on plasmids used for adeno-associated virus (AAV) manufacturing and data on AAV genome integrity, viral protein (VP) purity and VP ratios using the BioPhase 8800 system.
Last year, Technology Networks hosted two webinars that featured groundbreaking research utilizing SWATH DIA (data-independent acquisition) for exposomics and metabolomics. Researchers Dr. Vinicius Verri Hernandes from the University of Vienna and Dr. Cristina Balcells from Imperial College London (ICL) demonstrated how a DIA approach can be successfully implemented in small molecule analysis using the ZenoTOF 7600 system. Their innovative approaches highlight the potential of SWATH DIA to enhance the detection and analysis of chemical exposures and metabolites, paving the way for new insights into environmental health and disease mechanisms.
For as long as PFAS persist in the environment, there is no doubt they will persist in our conversations as environmental scientists. Globally, PFAS contamination has been detected in water supplies, soil and even in the blood of people and wildlife. Different countries are at various stages of addressing PFAS contamination and many governments have set regulatory limits and are working on assessing the extent of contamination, cleaning up affected sites and researching safer alternatives.
Posted by
nice
You must be logged in to post a comment.
Share this post with your network