PFAS explained: What they are, why they matter, and what’s changing

Jun 17, 2026 | Blogs, Environmental / Industrial, Food / Beverage | 0 comments

Read time: 2 minutes

PFAS are increasingly at the center of regulatory change, scientific research, and industry discussion worldwide. As analytical capabilities improve and expectations around environmental responsibility continue to evolve, understanding the role PFAS play, and how they are being addressed, has never been more important. This blog provides an overview of what PFAS are, why they matter, and how responses from regulators and industry are changing.

What are PFAS?

Per- and polyfluoroalkyl substances (PFAS) are a large group of humanmade chemicals that have been widely used for decades in industrial processes and consumer products. Valued for their resistance to heat, water, and oil, PFAS have played a role in everything from manufacturing and food packaging to textiles and firefighting foams.

However, these same properties have made PFAS a growing environmental and public health concern. Their persistence in the environment and living organisms has placed them firmly on the agenda for regulators, industries, and communities around the world.

PFAS include thousands of chemicals, some of which are termed “forever chemicals” because of their persistence in the environment. However, many PFAS degrade into other PFAS that are equally or more persistent. This leads to long-term presence in soil, water, air, wildlife, and the human body.

Their widespread historical use means PFAS are now present across many environmental systems. Advances in analytical testing continue to improve detection capabilities, revealing PFAS in places previously unrecognized, from groundwater and surface water to agricultural land and food systems.

Why do PFAS matter?

Scientific research has increasingly highlighted the potential risks associated with PFAS exposure. Certain substances within this chemical group have been linked to adverse health and environmental effects, prompting heightened concern and scrutiny.

Beyond health considerations, PFAS present long-term challenges for environmental management. Their persistence makes remediation technically complex and costly, while their mobility allows contamination to spread beyond its original source. As awareness grows, so do expectations for transparency, accountability, and effective risk mitigation.

What’s changing: Regulation and response

Regulatory attention to PFAS is intensifying globally. Many authorities are reviewing existing standards, introducing stricter limits, and expanding monitoring and reporting requirements. In some cases, specific PFAS are being restricted or phased out entirely.

Alongside regulatory changes, industry responses are accelerating. Organizations are investing in alternative materials, improved treatment technologies, and more robust environmental management practices. Collaboration across sectors – including science, policy, and industry – is increasingly recognized as essential to addressing PFAS challenges on a scale.

The need for clear information and practical resources

As understanding PFAS continues to evolve, access to reliable, up-to-date information is critical. Decision-makers need clarity on regulatory developments, emerging science, and practical approaches to monitoring, risk assessment, and remediation.

Whether working in environmental protection, food and agriculture, manufacturing, policy, or research, staying informed about PFAS is an important step toward making confident, responsible decisions in a rapidly changing landscape.

Curious to learn more?

Explore the SCIEX PFAS Hub >

Why SCIEX partners with experts around the world

Innovation in mass spectrometry does not happen in isolation. Some of the most impactful scientific advances emerge from highly specialized research communities – proteomics experts developing new peptide identification workflows, metabolomics researchers curating spectral databases, toxicologists building compound libraries, and biopharma scientists creating novel characterization methods.

Managing ADC characterization: The challenge of turning complexity into confidence

Unlike traditional monoclonal antibodies, ADCs combine an antibody backbone with linker chemistry and a cytotoxic payload. This multi-component architecture introduces overlapping layers of heterogeneity, including drug-to-antibody ratio (DAR) distributions, charge variants, post-translational modifications, and structural changes at both the intact and subunit levels. Across ADC development, these characteristics are considered critical quality attributes that must be characterized, understood, and monitored.

3 reasons ZT Scan DIA is changing the game in metabolomics

For years, metabolomics researchers have faced a frustrating reality: modern high-resolution mass spectrometers can detect tens of thousands of molecular features, yet only a fraction can be confidently identified. The challenge is no longer finding molecules. It is generating the high-quality MS/MS data needed to confidently assign structures and extract meaningful biological insights.

Posted by

Simon Roberts specializes in developing methods for PFAS analysis at SCIEX for both targeted and non-targeted analysis. Before working at SCIEX, Simon performed PFAS discovery research at Colorado School of Mines during his postdoctoral fellowship. He worked on projects that identified dozens of novel PFAS in groundwater and industrial chemicals. Recently, Simon has focused on educating the public about PFAS via his YouTube channel Environmental Chemistry Explained.

0 Comments

Submit a Comment

Pin It on Pinterest

Share This

Share this post with your network