GEN-MKT-18-7897-A
Dec 6, 2016 | Blogs, Food / Beverage | 0 comments
Are you looking for ways to up the ante on your LC-MS/MS when it comes to food testing? Researchers here have developed a method for the analysis of approximately 400 pesticides in food samples, and their work is available for viewing in this year’s compendium. This application note is just one of 16 you will find under Pesticides >
Using your QTRAP® LC-MS/MS System at its Full Potential OverviewUsing MRM mode, the QTRAP® 6500 LC-MS/MS was used to quantify hundreds of pesticides in food samples with high selectivity and sensitivity. Identification was further confirmed using MRM ratio identification. An alternative approach for compound identification went beyond the detection of multiple fragments.
Details of ExperimentTwenty pesticides were spiked into different food samples, and diluted extracts were analyzed using two methods.
Results and ConclusionsImproved data processing using a dual injection approach with automatic quantitation, identification, and confirmation using MasterView™ and MultiQuant™ Software. Results highlight the complementary nature of MRM ratios and MS/MS full scan offering a possibility of confirmatory analysis.
The Echo® MS+ system is a novel platform for Acoustic Ejection Mass Spectrometry (AEMS) and combines the speed of acoustic sampling with the selectivity of mass spectrometry. This platform has been designed for high throughput analysis of small and large molecules. The technology combines Acoustic Droplet Ejection (ADE), an Open Port Interface (OPI) and could be coupled with the SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system.
The Echo® MS+ system comprises of an open-port interface (OPI) and acoustic droplet ejection (ADE) module which could be coupled with a mass spectrometer. The mass spectrometer could either be a SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system. This non-liquid chromatography based; high-throughput screening platform enables rapid analysis of compounds at speeds of up to 1 sample/second.
The ability to consistently achieve reproducible results on many complex samples across multiple days is critical to a routine clinical laboratory. Laboratories relying on analytical instrumentation require stability and robustness to perform a variety of screening and confirmatory assays with confidence. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the preferred analytical method in the clinical laboratory to reliably perform clinical testing as it provides best-in-class performance and reliability for the most challenging assays. LC-MS/MS offers the required levels of sensitivity and specificity for the detection and quantitation of molecules from complex biological samples, helping laboratories deliver highly accurate data for a variety of clinically relevant analytes across a wide range of assays.
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