PPCP Detection in Drinkwater is no Match for the QTRAP® 5500

Feb 14, 2017 | Blogs, Environmental / Industrial | 0 comments

SCIEX is no stranger to drinking water analysis, and the Environmental Compendium once again addresses the topic in an application note which covers LC-MS/MS with Fast Polarity Switching.   Using the QTRAP® 5500, researchers were able to detect a large panel of Pharmaceuticals and Personal Care Products (PPCP’s) while performing fast positive/negative switching all from a single injection.  Method details go the distance in this application note, as five experiments were called into action for comparison.Download Environmental Compendium >

Why Test for PPCP’s in Drinking water?
Not all wastewater treatment processes are created equal and can leave behind trace amounts of influent PPCP’s. While the amounts are considered minimal, they have been known to cause disruption to aquatic life, thus the reason for ultra-low analysis in the lab. Numbers vary, but thousands of PPCP’s are known to be in existence and depending on the substance, some have shorter shelf lives than others. Insulin, for example, can expire as soon as 30 days after a bottle is open and if flushed, can enter freshwater if removal isn’t effective at the treatment plant. We may not be able to live without our pharmaceuticals and personal care products, but in the Environmental Compendium, researchers report how you can better test fresh water samples for PPCP’s in the parts per trillion range.

Want to learn more about PPCP analysis? The Environmental Compendium has pages of application notes dedicated to the topic, and we want to share them with you!

Want to learn how to dispose of PPCP’s properly? Check with your local resources. Many communities have days where you can drop off the used medicine.

Understanding PFAS and its impact on U.S. drinking water

In recent years, per- and polyfluoroalkyl substances (PFAS), often referred to as “forever chemicals,” have become a growing topic of interest due to their persistence in the environment and potential health risks. These synthetic compounds have been widely used in various industrial applications and consumer products since the 1940s. PFAS can be found in the air, soil, and water, and studies have shown that most people have detectable levels of PFAS in their bloodstream. One of the main exposure pathways for humans is through drinking water, particularly in communities located near industrial sites, military bases, or areas where firefighting foam has been used.

Selecting an LC-MS system for quantitation of pharmaceutical drug development

We understand you are busy, needing to prioritize running instruments, reporting results and managing your laboratory to meet deadlines. We created a solution guide to explain how SCIEX systems fit in the drug development pipeline to save you time evaluating options.

Nitrosamines: Where are we now?

Nitrosamines are a large group of N-nitroso compounds that share a common functional N-N=O group. They are produced by a chemical reaction between a nitrosating agent and a secondary or tertiary amine. Back in 2018, nitrosamines suddenly found themselves in the spotlight when they were unexpectedly detected in medications for high blood pressure. Since then, they have been found in several other prescription medications, including those for heartburn, acid reflux and diabetes, resulting in manufacturers recalling some common medications.

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