PPCP Detection in Drinkwater is no Match for the QTRAP® 5500

Feb 14, 2017 | Blogs, Environmental / Industrial | 0 comments

SCIEX is no stranger to drinking water analysis, and the Environmental Compendium once again addresses the topic in an application note which covers LC-MS/MS with Fast Polarity Switching.   Using the QTRAP® 5500, researchers were able to detect a large panel of Pharmaceuticals and Personal Care Products (PPCP’s) while performing fast positive/negative switching all from a single injection.  Method details go the distance in this application note, as five experiments were called into action for comparison.Download Environmental Compendium >

Why Test for PPCP’s in Drinking water?
Not all wastewater treatment processes are created equal and can leave behind trace amounts of influent PPCP’s. While the amounts are considered minimal, they have been known to cause disruption to aquatic life, thus the reason for ultra-low analysis in the lab. Numbers vary, but thousands of PPCP’s are known to be in existence and depending on the substance, some have shorter shelf lives than others. Insulin, for example, can expire as soon as 30 days after a bottle is open and if flushed, can enter freshwater if removal isn’t effective at the treatment plant. We may not be able to live without our pharmaceuticals and personal care products, but in the Environmental Compendium, researchers report how you can better test fresh water samples for PPCP’s in the parts per trillion range.

Want to learn more about PPCP analysis? The Environmental Compendium has pages of application notes dedicated to the topic, and we want to share them with you!

Want to learn how to dispose of PPCP’s properly? Check with your local resources. Many communities have days where you can drop off the used medicine.

New EPA Method 563: Taking on the challenge of ultrashort-chain PFAS

 PFAS testing is entering a new phase. With seven ultrashort-chain organofluorine compounds included in EPA Method 563, drinking water laboratories face a new set of analytical challenges, from poor chromatographic retention and background contamination to limited fragmentation.

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As PFAS testing continues to expand, laboratories face increasing pressure to deliver reliable results at lower detection limits and faster turnaround times. While much of the conversation focuses on analytical methods and regulations, maintaining instrument performance and minimizing downtime are equally critical to success.

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Whether supporting pharmaceutical quality control, bioanalysis, clinical research, environmental testing, or food safety applications, regulated laboratories share a common responsibility: ensuring reliable data, maintaining audit readiness, and controlling systems throughout their lifecycle. Yet when compliance discussions arise, attention often moves quickly to audits, documentation, electronic records, and standard operating procedures. These elements are essential, but they depend on a more fundamental question: Can the analytical system consistently produce reliable results?

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