The Technology Behind Safe, Legal Cannabis

Jan 14, 2019 | Blogs, Food / Beverage | 0 comments

The Third in a Three-Part Series

Part 1: Cannabis is Legal in Canada – How Did We Get Here?  
Part 2: Canada’s Focus on Cannabis Quality and Safety Intensifies 

Welcome to the third in a series of blogs from the cannabis team at SCIEX, designed to bring you up to speed and put you in the lead of the recently legalized cannabis market in Canada.

‘Protecting public health and safety by allowing adults access to legal cannabis’ is high on Health Canada’s agenda. In the last blog, we explored the tests involved in ensuring legal cannabis is safe, here we will examine the technology behind these tests.

What the Analytical Testing Lab Needs to Know
Whether cultivation, processing, analyzing or selling, anyone planning to operate in the market must be a cannabis license holder under the Act. Legal cannabis products must be produced within the rules of the law and undergo rigorous testing before they can be made available to the public.

Regulatory standards for cannabis testing are expected to evolve, and it would be fair to say that the cannabis testing landscape is not only uncertain, but it is complex. Here’s a quick rundown on where things stand at the time of writing this blog:

  • Laboratories certified for analytical testing must conduct all tests using validated methods on every lot or batch of cannabis to ensure regulatory requirements are met
  • There are already rules for testing in place for medical marijuana, but these are expected to become more comprehensive and stringent – watch this space
  • Testing depends on the cannabis product class, but will typically include potency, terpenes, pesticides, and contaminants such as heavy metals, solvents, and mycotoxins
  • While there are industry-wide rules and standards, different provinces and territories will set their own legislation action limits or acceptable maximum residual levels
  • Complex analytical characteristics of the plant mean labs need to quantify many residues with dirty matrices and handle sample variation depending on the cannabis product class
  • There simply aren’t enough labs to keep up with the volume of samples and the demand for testing services is expected to rocket

With the challenges outlined above, the question is:

What Techniques Best Suit These Testing Demands?
Labs need the right instruments and methods to stay ahead of regulation, keep up with demand and deliver fast and reliable results – better than the competition. We believe this can be achieved with the most advanced technologies that offer high-throughput validated methods for accurate results, with complete workflows that combine tests into a single analysis.

The industry is now turning to instruments that are proven in more established applications, such as food and pharma, and have already been applied to cannabis testing with great success. High-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) is one of these technologies.

Cannabis has historically been monitored by gas chromatography-mass spectrometry (GC-MS) requiring complicated sample preparation with derivatization and relatively long sample run times. LC-MS/MS has now emerged as one of the most reliable and robust high-throughput analytical methods available, tackling the demands of cannabis testing head on.

How We Can Help
SCIEX offers everything licensed analytical testing labs, regulatory laboratories, and licensed producers need to perform a wide variety of tests to Health Canada standards while cutting tests down to record time.

We have pioneered standardized testing methods that enable you to overcome the complex analytical nature of cannabis in regulated markets. Best-in-class LC-MS/MS technology has been applied to potency, terpene, pesticide, and contaminant analysis, allowing you to match all chemical residues to the lower possible limit, within a single instrument. Users experience superior selectivity, sensitivity, and ruggedness without extensive sample preparation.

To help your lab meet demand and get ahead of new regulations, we have put together an exclusive free cannabis testing info kit packed with useful information, including methods and solutions to common screening challenges.

Fill out the form on your right to download the info kit, and take the first step towards fast, accurate, and compliant cannabis testing.

 

Understanding PFAS and its impact on U.S. drinking water

In recent years, per- and polyfluoroalkyl substances (PFAS), often referred to as “forever chemicals,” have become a growing topic of interest due to their persistence in the environment and potential health risks. These synthetic compounds have been widely used in various industrial applications and consumer products since the 1940s. PFAS can be found in the air, soil, and water, and studies have shown that most people have detectable levels of PFAS in their bloodstream. One of the main exposure pathways for humans is through drinking water, particularly in communities located near industrial sites, military bases, or areas where firefighting foam has been used.

Selecting an LC-MS system for quantitation of pharmaceutical drug development

We understand you are busy, needing to prioritize running instruments, reporting results and managing your laboratory to meet deadlines. We created a solution guide to explain how SCIEX systems fit in the drug development pipeline to save you time evaluating options.

Nitrosamines: Where are we now?

Nitrosamines are a large group of N-nitroso compounds that share a common functional N-N=O group. They are produced by a chemical reaction between a nitrosating agent and a secondary or tertiary amine. Back in 2018, nitrosamines suddenly found themselves in the spotlight when they were unexpectedly detected in medications for high blood pressure. Since then, they have been found in several other prescription medications, including those for heartburn, acid reflux and diabetes, resulting in manufacturers recalling some common medications.

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