GEN-MKT-18-7897-A
Feb 24, 2020 | Blogs, Food / Beverage | 0 comments
Fast, accurate, and robust solution for routine commercial cannabis testing
As the world debates cannabis legalization for therapeutic applications and recreational use, the trends are shifting. Medicinal use of cannabis is legal in an increasing number of countries worldwide, including 33 states and the District of Columbia in the United States. Uruguay was the first country in the world to legalize the sale, cultivation, and distribution of cannabis in 2013. In the United States, Washington and Colorado were the first to fully legalize cannabis in 2012. By the end of 2019, 10 states have legalized recreational use for adults over the age of 21, with 64% of Americans favoring the move.
Source: ProCon.org
In the past, cannabis agriculture has been completely unregulated, with distribution driven by unlawful dispensaries. However, with legalization, this industry is rapidly blooming. While the trend is celebrated by campaigners worldwide, concerns around public safety are increasing. For one thing, not all cannabis that hits the shelves is safe. There’s a possibility that these products are laced with contaminants, or that they are so potent that they are not safe for consumption.
Cannabis testing for safetyAccurate testing is a critical piece to help ensure consumer safety. Your lab needs robust methods for routine commercial analysis to test your marijuana and hemp samples for:
With public safety a primary concern for regulators, it comes as no surprise that regulators are clamping down on dispensaries. With legalization in the United States defined by each state, there is varying legislation indicating what needs to be monitored and at what levels. The legislation also specifies action limits or maximum residue limits (MRLs) that must not be exceeded. Screening has become a prerequisite, and cannabis testing labs are feeling the strain.
Where mass spectrometry plays a role in cannabis testing technology
Early liquid chromatography with tandem mass spectrometry (LC-MS/MS) methods were developed primarily for residue analysis of pesticides, herbicides, plant growth regulators and mycotoxins. These methods cover a wider range of compounds than gas chromatography-mass spectrometry (GC/MS) methods and offer more sensitivity, robustness and productivity. In later years, we’ve seen other LC-MS/MS methodologies and applications developed that easily and accurately quantify cannabinoids. This includes high-resolution accurate mass (HRMS) techniques that prove to be useful in chemovar identification, and also analysis using QTRAP® systems, which offer the increased specificity of MRM3 scans.
We understand that cannabis poses its own set of unique testing challenges. From setting up a lab and developing methods for the analysis of cannabis plants and products, to keeping up with emerging regulations, it’s an ever-changing landscape. Whether you’re in a reference lab, an in-house testing lab or supporting law enforcement, you need the right technology, method and partner to drive exceptional return on investment.
Click the banner above to access the compendium on global marijuana and hemp trends and landmark analytical research on the following topics:
About me, Paul WinklerI play an active role in supporting cannabis (marijuana and hemp) applications at SCIEX. I have more than 30-years of experience owning and operating contract labs in the environmental and bioanalytical markets. I’ve been part of the SCIEX family since 2011; started as a field application chemist and today I’m a market development manager for the North America team; helping customers like you with your analytical challenges and educating the market on the many possibilities of LC-MS/MS systems is my passion.
The Echo® MS+ system is a novel platform for Acoustic Ejection Mass Spectrometry (AEMS) and combines the speed of acoustic sampling with the selectivity of mass spectrometry. This platform has been designed for high throughput analysis of small and large molecules. The technology combines Acoustic Droplet Ejection (ADE), an Open Port Interface (OPI) and could be coupled with the SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system.
The Echo® MS+ system comprises of an open-port interface (OPI) and acoustic droplet ejection (ADE) module which could be coupled with a mass spectrometer. The mass spectrometer could either be a SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system. This non-liquid chromatography based; high-throughput screening platform enables rapid analysis of compounds at speeds of up to 1 sample/second.
The ability to consistently achieve reproducible results on many complex samples across multiple days is critical to a routine clinical laboratory. Laboratories relying on analytical instrumentation require stability and robustness to perform a variety of screening and confirmatory assays with confidence. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the preferred analytical method in the clinical laboratory to reliably perform clinical testing as it provides best-in-class performance and reliability for the most challenging assays. LC-MS/MS offers the required levels of sensitivity and specificity for the detection and quantitation of molecules from complex biological samples, helping laboratories deliver highly accurate data for a variety of clinically relevant analytes across a wide range of assays.
Posted by
You must be logged in to post a comment.
Share this post with your network