GEN-MKT-18-7897-A
Oct 11, 2017 | Blogs, Technology | 0 comments
If you are working with complex assays that demand exceptionally selective quantitative and qualitative performance, sometimes even the most powerful LC-MS/MS technology can’t always cut it alone.
Perhaps you are struggling to separate isobaric species, isolate challenging co-eluting analytes or reduce high background noise? Regardless of your challenge, the outcome is the same. You probably aren’t getting the levels of quantitation or characterization you need, so method development has become cumbersome, and workflow performance is suffering.
Now you can bring a new dimension of selectivity to your LC-MS/MS analysis on select SCIEX Triple Quad™, QTRAP® and TripleTOF® Systems with SelexION® Differential Mobility Separation (DMS) Technology. The SelexION DMS cell:
Harness the power of differential mobility separations to simplify your sample preparations, while achieving unprecedented levels of selectivity. Find out more by downloading the SelexION brochure.
How does it work?Gas phase differential mobility separation within the SelexION device planar mobility cell is based on the ion’s size and shape, and the difference between their unique differential mobilities across high and low energy fields. Gas phase separation occurs prior to entering the mass analyzer where the compounds are then further separated by m/z ratios.
Depending on the samples that you are running on the system, it is possible for the Echo MS electrode to become dirty or occluded over time. Below are two different cleaning strategies that will be helpful for you to maintain your system and keep your electrodes running well.
Developing an analytical method can be one of the most rewarding jobs an analytical scientist can do, but it can also be one of the most complex and frustrating. To help guide your practical experiments and thought processes we spoke to Kean Woodmansey to benefit from his experience.
As analytical organizations grow, there is an even greater need to train scientists and operators more consistently to meet tight deadlines, handle increasing samples, and meet data quality expectations. A high rate of employee turnover also affects the productivity of labs worldwide. Consistent training helps today’s labs stay competitive, whether the goal is sample throughput, therapeutic development, or publication.
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