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Oct 31, 2015 | Blogs, Food / Beverage | 0 comments
Halloween is the time for lots of trick or treats ranging from chocolate bars to lollipops and oh so good candy corn. However, come October 31, it is time to mind sneaky ingredients that have the best disguise of all. From pork extracts, artificial sweeteners, to stuff that is hard to pronounce, SCIEX digs up some of our recent Food and Beverage studies for some ghoulishly good fun.
Where do Gummy Bears get their Squishiness From?
Gummy bears have to get their gelatinous shape from somewhere, and that somewhere happens to be collagen extracted from skin, bones and connective tissue of cows, chickens, pigs, and fish. ELISA testing, which is typically used to detect these animal proteins in your favorite gummy treats, can produce false negatives or positives in that animal protein markers may not be detected or accurately identified. Now, if only the wrapper read it was tested in a lab using LC-MS/MS could you be more certain your gummy bears and any other candies containing gelatin were pork-free. Read the complete study here.
What do Plastics and Candy have to do with One Another?
Up next are Phthalates, a chemical agent found in plastics that makes them more bendable or harder to break. What does this have to do with candy? Some derivatives are used in wrappers and while it is unknown how much exposure can cause a health risk, some forms have been blamed for endocrine disruption in rats. However, it is not just candy wrappers you will find phthalates in, as it migrates from most packaging to foods. If you are interested in knowing how LC-MS/MS can enhance the detection of phthalates in food and beverage samples, we have the study for you.
Artifical Sweeteners Be Gone
Then there are artificial sweeteners that are better for your teeth and waistline but could cause your trick or treater to crave even more sweets. Sigh. To be sure the label is as true as its ingredients reliable detection is needed. This is where one SCIEX study proved useful as LC-MS/MS proves to be five times faster as well as more than 100 to 1000 fold more sensitive than traditional LC methods.
It is no secret that (bio)pharmaceutical research and development is complex, both scientific and regulatory processes. Here is an overview of just some of the ways SCIEX is working to support these challenges.
In a recent webinar, available on demand, scientists Luiza Chrojan and Ryan Hylands from Pharmaron, provided insights into the deployment of capillary gel electrophoresis (CGE) within cell and gene therapy. Luiza and Ryan shared purity data on plasmids used for adeno-associated virus (AAV) manufacturing and data on AAV genome integrity, viral protein (VP) purity and VP ratios using the BioPhase 8800 system.
Last year, Technology Networks hosted two webinars that featured groundbreaking research utilizing SWATH DIA (data-independent acquisition) for exposomics and metabolomics. Researchers Dr. Vinicius Verri Hernandes from the University of Vienna and Dr. Cristina Balcells from Imperial College London (ICL) demonstrated how a DIA approach can be successfully implemented in small molecule analysis using the ZenoTOF 7600 system. Their innovative approaches highlight the potential of SWATH DIA to enhance the detection and analysis of chemical exposures and metabolites, paving the way for new insights into environmental health and disease mechanisms.
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