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Top Three Ways SCIEX has fun with Halloween Candy

Oct 31, 2015 | Blogs, Food / Beverage | 0 comments

Halloween is the time for lots of trick or treats ranging from chocolate bars to lollipops and oh so good candy corn. However, come October 31, it is time to mind sneaky ingredients that have the best disguise of all. From pork extracts, artificial sweeteners, to stuff that is hard to pronounce, SCIEX digs up some of our recent Food and Beverage studies for some ghoulishly good fun.

Where do Gummy Bears get their Squishiness From?

Gummy bears have to get their gelatinous shape from somewhere, and that somewhere happens to be collagen extracted from skin, bones and connective tissue of cows, chickens, pigs, and fish. ELISA testing, which is typically used to detect these animal proteins in your favorite gummy treats, can produce false negatives or positives in that animal protein markers may not be detected or accurately identified. Now, if only the wrapper read it was tested in a lab using LC-MS/MS could you be more certain your gummy bears and any other candies containing gelatin were pork-free. Read the complete study here.

What do Plastics and Candy have to do with One Another?

Up next are Phthalates, a chemical agent found in plastics that makes them more bendable or harder to break. What does this have to do with candy? Some derivatives are used in wrappers and while it is unknown how much exposure can cause a health risk, some forms have been blamed for endocrine disruption in rats. However, it is not just candy wrappers you will find phthalates in, as it migrates from most packaging to foods.  If you are interested in knowing how LC-MS/MS can enhance the detection of phthalates in food and beverage samples, we have the study for you.

Artifical Sweeteners Be Gone

Then there are artificial sweeteners that are better for your teeth and waistline but could cause your trick or treater to crave even more sweets. Sigh. To be sure the label is as true as its ingredients reliable detection is needed. This is where one SCIEX study proved useful as LC-MS/MS proves to be five times faster as well as more than 100 to 1000 fold more sensitive than traditional LC methods.

Supporting new CRISPR gene editing systems

Prime editing (PE) is a next-generation gene editing technology that utilizes a Cas9 protein fused to a prime editing guide ribonucleic acid (pegRNA) to achieve high CRISPR/Cas9 editing efficiency and precision. However, the length requirement of pegRNAs at 120–250 nucleotides (nt) and their high level of secondary structure formation present analytical challenges for the purity analysis of chemically synthesized pegRNAs during development and quality control (QC).

A new approach for comprehensive AAV evaluation including full and empty analysis

Certain next-gen vaccines and gene therapy applications rely on the usage of adeno-associated viruses (AAV) as a delivery vehicle. To ensure the safety and efficacy of viral vector drugs, multiple critical quality attributes (CQAs) need to be well characterized.

The rising tide of food allergies: Common questions and crucial insights

Allergy policies for nut-free commercial flights and nut-free childcare settings are not a rare occurrence nowadays—the reason is a rise in food allergies. Nuts are the most potent allergenic foods in terms of the amount that is required to elicit an allergic reaction and the severity of those reactions.

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