GEN-MKT-18-7897-A
Oct 31, 2015 | Blogs, Food / Beverage | 0 comments
Halloween is the time for lots of trick or treats ranging from chocolate bars to lollipops and oh so good candy corn. However, come October 31, it is time to mind sneaky ingredients that have the best disguise of all. From pork extracts, artificial sweeteners, to stuff that is hard to pronounce, SCIEX digs up some of our recent Food and Beverage studies for some ghoulishly good fun.
Where do Gummy Bears get their Squishiness From?
Gummy bears have to get their gelatinous shape from somewhere, and that somewhere happens to be collagen extracted from skin, bones and connective tissue of cows, chickens, pigs, and fish. ELISA testing, which is typically used to detect these animal proteins in your favorite gummy treats, can produce false negatives or positives in that animal protein markers may not be detected or accurately identified. Now, if only the wrapper read it was tested in a lab using LC-MS/MS could you be more certain your gummy bears and any other candies containing gelatin were pork-free. Read the complete study here.
What do Plastics and Candy have to do with One Another?
Up next are Phthalates, a chemical agent found in plastics that makes them more bendable or harder to break. What does this have to do with candy? Some derivatives are used in wrappers and while it is unknown how much exposure can cause a health risk, some forms have been blamed for endocrine disruption in rats. However, it is not just candy wrappers you will find phthalates in, as it migrates from most packaging to foods. If you are interested in knowing how LC-MS/MS can enhance the detection of phthalates in food and beverage samples, we have the study for you.
Artifical Sweeteners Be Gone
Then there are artificial sweeteners that are better for your teeth and waistline but could cause your trick or treater to crave even more sweets. Sigh. To be sure the label is as true as its ingredients reliable detection is needed. This is where one SCIEX study proved useful as LC-MS/MS proves to be five times faster as well as more than 100 to 1000 fold more sensitive than traditional LC methods.
In biopharmaceutical development, sequence variants (SV) are considered an inherent risk of producing complex proteins in living systems. Sequence variants are unintended changes to the amino acid sequence of a biotherapeutic and can be caused by errors in transcription or translation in the host cell, or cell culture and process conditions. Detailed analysis of SVs is important in process and product development to ensure the drug’s safety and efficacy. Even low‑level sequence variants can have significant implications for product quality, safety, and efficacy, making their accurate detection and characterization a critical requirement across development, process optimization, and regulatory submission.
CE‑SDS remains a cornerstone assay for characterizing fragmentation, aggregation, and product‑related impurities in therapeutic proteins. UV detection has been the long‑standing standard. However, it frequently struggles with baseline noise, limited sensitivity for minor fragments, and subjective integration.
At SCIEX, innovation doesn’t stop at instruments; it extends to how you interact with your LC-MS/MS or CE systems every day. That’s why we’re excited to introduce the SCIEX Now spring 2026 improvements: a set of meaningful enhancements shaped directly by your feedback.
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