GEN-MKT-18-7897-A
May 13, 2016 | Blogs, Food / Beverage | 0 comments
Recent regulations on food analysis require screening for pesticides using confirmatory techniques, such as GC-MS and LC-MS/MS. More than 1000 pesticides are used worldwide and, along with their metabolites and degradation products, are present in food. There is a demand for powerful and rapid analytical methods that can identify pesticides with high confidence in a broad range of food matrices and quantify at low concentrations with good accuracy and reproducibility. Challenges for pesticide residue laboratories at the moment are the request to test for more compounds, in a wider range of samples, all without sacrificing data quality. The QTRAP® 6500 LC-MS/MS system uses multi-component IonDrive™ technology to:
In addition, the QTRAP 6500 system uses the patented and proven Linear Accelerator™ trap technology to:
A new method for the quantitation and identification of hundreds of pesticides in food samples was developed and successfully applied to the analysis of complex food samples using the QTRAP 6500 system. Results are compared to QTRAP 5500 data. The increased sensitivity was used to extensively dilute sample extracts to eliminate ion suppression caused by matrix components and the extended linear dynamic range allowed quantifying more pesticides across a wider range of chemical properties. QTRAP scanning was used to investigate the presence of matrix components and to identify targets with high confidence through library searching. Quantitative and qualitative results were generated using MultiQuant™ and LibraryView™ Software.
See the results in the full article by downloading the Food Compendium.
Last year, Technology Networks hosted two webinars that featured groundbreaking research utilizing SWATH DIA (data-independent acquisition) for exposomics and metabolomics. Researchers Dr. Vinicius Verri Hernandes from the University of Vienna and Dr. Cristina Balcells from Imperial College London (ICL) demonstrated how a DIA approach can be successfully implemented in small molecule analysis using the ZenoTOF 7600 system. Their innovative approaches highlight the potential of SWATH DIA to enhance the detection and analysis of chemical exposures and metabolites, paving the way for new insights into environmental health and disease mechanisms.
For as long as PFAS persist in the environment, there is no doubt they will persist in our conversations as environmental scientists. Globally, PFAS contamination has been detected in water supplies, soil and even in the blood of people and wildlife. Different countries are at various stages of addressing PFAS contamination and many governments have set regulatory limits and are working on assessing the extent of contamination, cleaning up affected sites and researching safer alternatives.
On average, it takes 10-15 years and 1-2 billion dollars to approve a new pharmaceutical for clinical use. Since approximately 90% of new drug candidates fail in clinical development, the ability to make early, informed and accurate decisions on the safety and efficacy of new hits and leads is key to increasing the chances of success.
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