GEN-MKT-18-7897-A
Dec 16, 2016 | Blogs, Food / Beverage | 0 comments
Ever wish you had access to the most up to date application methods but don’t know where to find them? The Food and Beverage Compendium is your one-stop resource for research notes ranging from pesticides, allergens, and antibiotics to mycotoxins, vitamins, and packaging. An example of what you can find inside includes the detection of pesticide 1080 (sodium fluoroacetate), as a food contaminant in milk and infant formula, which New Zealand is heavily dependent upon to control its rodent population.
The reason for this research concerns a 2014 threat, in which letters containing milk powder were sent to the New Zealand farming and dairy industry leaders containing a concentrated version of 1080 used for pest control. Accordingly, only cyanide is more powerful when it comes to killing pests, but is also dangerous to humans. Pesticide 1080 is reportedly biodegradable and does not remain in soil or waterways. An alternative to 1080 application is trapping, which is labor intensive and supply driven.
Therefore, to offer labs a viable way to test for the presence of 180, a liquid chromatography method coupled with tandem mass spectrometry (LC-MS/MS) was used as an analytical technique to detect polar analytes in complex food samples. You can find out more about the process in which the-the SCIEX QTRAP® 4500 System with Turbo V™ source was operated using an ESI probe in negative polarity by downloading the entire compendium. It is just one of 16 research notes dedicated to pesticides.Download The Food Compendium >
In monoclonal antibody (mAb) development, assessment of purity and integrity of the protein in question is critical. CE‑SDS is the gold standard assay and is routinely run from analytical development through QC and lot release. It’s trusted because it consistently delivers quantitative, size‑based insight into purity and fragmentation, and it fits naturally into regulated environments.
In drug discovery and development, Metabolite Identification (Met ID) plays a critical role in understanding biotransformation pathways, ensuring safety, and meeting regulatory requirements. Advanced mass spectrometry techniques have revolutionized this process, particularly through electron-based fragmentation methods such as Electron Activated Dissociation (EAD) and Electron Transfer Dissociation (ETD). While both techniques leverage electron interactions to generate informative fragment ions, they differ significantly in mechanism, performance, and suitability for Met ID workflows.
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