GEN-MKT-18-7897-A
Dec 16, 2016 | Blogs, Food / Beverage | 0 comments
Ever wish you had access to the most up to date application methods but don’t know where to find them? The Food and Beverage Compendium is your one-stop resource for research notes ranging from pesticides, allergens, and antibiotics to mycotoxins, vitamins, and packaging. An example of what you can find inside includes the detection of pesticide 1080 (sodium fluoroacetate), as a food contaminant in milk and infant formula, which New Zealand is heavily dependent upon to control its rodent population.
The reason for this research concerns a 2014 threat, in which letters containing milk powder were sent to the New Zealand farming and dairy industry leaders containing a concentrated version of 1080 used for pest control. Accordingly, only cyanide is more powerful when it comes to killing pests, but is also dangerous to humans. Pesticide 1080 is reportedly biodegradable and does not remain in soil or waterways. An alternative to 1080 application is trapping, which is labor intensive and supply driven.
Therefore, to offer labs a viable way to test for the presence of 180, a liquid chromatography method coupled with tandem mass spectrometry (LC-MS/MS) was used as an analytical technique to detect polar analytes in complex food samples. You can find out more about the process in which the-the SCIEX QTRAP® 4500 System with Turbo V™ source was operated using an ESI probe in negative polarity by downloading the entire compendium. It is just one of 16 research notes dedicated to pesticides.Download The Food Compendium >
In biopharmaceutical development, sequence variants (SV) are considered an inherent risk of producing complex proteins in living systems. Sequence variants are unintended changes to the amino acid sequence of a biotherapeutic and can be caused by errors in transcription or translation in the host cell, or cell culture and process conditions. Detailed analysis of SVs is important in process and product development to ensure the drug’s safety and efficacy. Even low‑level sequence variants can have significant implications for product quality, safety, and efficacy, making their accurate detection and characterization a critical requirement across development, process optimization, and regulatory submission.
CE‑SDS remains a cornerstone assay for characterizing fragmentation, aggregation, and product‑related impurities in therapeutic proteins. UV detection has been the long‑standing standard. However, it frequently struggles with baseline noise, limited sensitivity for minor fragments, and subjective integration.
At SCIEX, innovation doesn’t stop at instruments; it extends to how you interact with your LC-MS/MS or CE systems every day. That’s why we’re excited to introduce the SCIEX Now spring 2026 improvements: a set of meaningful enhancements shaped directly by your feedback.
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