GEN-MKT-18-7897-A
Mar 17, 2017 | Biopharma, Blogs | 0 comments
There is a lot of talk going around in the lab, and it has to do with the newly released Fast Glycan Labeling and Analysis technology. Where once research analysts needed to set aside days to perform glycan analysis, now takes an hour or so. Glycans are immediately identified by the software – so no need for data interpretation. That’s up to 5x faster than HILIC.
Short and simple 60-minute sample prep, followed by a 5-minute high-resolution separation provide immediate glycan identification and quantitation. Since glycan identification is automated, the Fast Glycan technology also eliminates the need for manual database searches while removing the potential for human error from the process.
Bioprocess International recognized our Fast Glycan technology and awarded it the 2016 Best Technology Application – Analytical Award.
Based on magnetic bead technology, it does not require centrifugation or advanced pipetting techniques, making the assay suitable for manual pipetting as well as automation. Researchers can, therefore, quickly detect changes in glycosylation, helping profile glycans that may effect changes in function, efficacy, and clearance of their biologics.
What does this mean for your lab, and how can you test the process yourself? To help you better understand the process, researchers documented the Fast Glycan Labeling and Analysis technology for N-glycosylation analysis in the following application note, “High-Resolution Separation and Identification in Minutes.”
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For research use only. Not for use in diagnostic procedures.
Last year, Technology Networks hosted two webinars that featured groundbreaking research utilizing SWATH DIA (data-independent acquisition) for exposomics and metabolomics. Researchers Dr. Vinicius Verri Hernandes from the University of Vienna and Dr. Cristina Balcells from Imperial College London (ICL) demonstrated how a DIA approach can be successfully implemented in small molecule analysis using the ZenoTOF 7600 system. Their innovative approaches highlight the potential of SWATH DIA to enhance the detection and analysis of chemical exposures and metabolites, paving the way for new insights into environmental health and disease mechanisms.
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On average, it takes 10-15 years and 1-2 billion dollars to approve a new pharmaceutical for clinical use. Since approximately 90% of new drug candidates fail in clinical development, the ability to make early, informed and accurate decisions on the safety and efficacy of new hits and leads is key to increasing the chances of success.
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