GEN-MKT-18-7897-A
Mar 17, 2017 | Biopharma, Blogs | 0 comments
There is a lot of talk going around in the lab, and it has to do with the newly released Fast Glycan Labeling and Analysis technology. Where once research analysts needed to set aside days to perform glycan analysis, now takes an hour or so. Glycans are immediately identified by the software – so no need for data interpretation. That’s up to 5x faster than HILIC.
Short and simple 60-minute sample prep, followed by a 5-minute high-resolution separation provide immediate glycan identification and quantitation. Since glycan identification is automated, the Fast Glycan technology also eliminates the need for manual database searches while removing the potential for human error from the process.
Bioprocess International recognized our Fast Glycan technology and awarded it the 2016 Best Technology Application – Analytical Award.
Based on magnetic bead technology, it does not require centrifugation or advanced pipetting techniques, making the assay suitable for manual pipetting as well as automation. Researchers can, therefore, quickly detect changes in glycosylation, helping profile glycans that may effect changes in function, efficacy, and clearance of their biologics.
What does this mean for your lab, and how can you test the process yourself? To help you better understand the process, researchers documented the Fast Glycan Labeling and Analysis technology for N-glycosylation analysis in the following application note, “High-Resolution Separation and Identification in Minutes.”
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For research use only. Not for use in diagnostic procedures.
The Echo® MS+ system is a novel platform for Acoustic Ejection Mass Spectrometry (AEMS) and combines the speed of acoustic sampling with the selectivity of mass spectrometry. This platform has been designed for high throughput analysis of small and large molecules. The technology combines Acoustic Droplet Ejection (ADE), an Open Port Interface (OPI) and could be coupled with the SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system.
The Echo® MS+ system comprises of an open-port interface (OPI) and acoustic droplet ejection (ADE) module which could be coupled with a mass spectrometer. The mass spectrometer could either be a SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system. This non-liquid chromatography based; high-throughput screening platform enables rapid analysis of compounds at speeds of up to 1 sample/second.
The ability to consistently achieve reproducible results on many complex samples across multiple days is critical to a routine clinical laboratory. Laboratories relying on analytical instrumentation require stability and robustness to perform a variety of screening and confirmatory assays with confidence. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the preferred analytical method in the clinical laboratory to reliably perform clinical testing as it provides best-in-class performance and reliability for the most challenging assays. LC-MS/MS offers the required levels of sensitivity and specificity for the detection and quantitation of molecules from complex biological samples, helping laboratories deliver highly accurate data for a variety of clinically relevant analytes across a wide range of assays.
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