GEN-MKT-18-7897-A
Jun 5, 2017 | Blogs, Pharma | 0 comments
If you work in the breakneck world of therapeutic development, then you probably don’t even have time to read this blog (but we thought we would write it anyways, just in case). Drug metabolism samples are coming into your lab fast and furious. You need to turn them around in hours so that chemists and biologists can optimize the effectiveness of the therapeutic candidate. Time for lunch? We don’t think so!
The chances are that you know about high-throughput LC-MS techniques, you probably even know that you need to adopt them, but where do you start? We know how demanding routine biotransformation studies can be, so we have done our best to make this as easy for you as possible with a solution that came from very clear objectives.
We wanted to help you maximize compound analysis while reducing method development time. We wanted to impress you with fast, automated data processing to identify the top metabolites and soft spots. We wanted to give you absolute confidence in the data report, and in a format that a medicinal chemist would like to see. We wanted to give you assurances in instrument uptime so you can just focus on getting the answers you need. We wanted you to have time for lunch!
We bring you the Routine Biotransform Solution, a simple and streamlined platform for high-throughput MetID analyses for both small and large molecule therapeutics. The compact, easy-to-use instrumentation and powerful automated data processing software helps you achieve new levels of productivity and throughput to boost performance and keep your projects moving.
We have crammed in as much of our best-in-class LC-MS technology as we possibly can, making routine ID of the top metabolites and biotherapeutic catabolites as simple and fast as possible. Fully integrated into one complete solution, you benefit from:
We know it is a lot to take in, but if you need high-throughput, then you need a solution as powerful as the Routine Biotransform Solution from SCIEX. For further information on how you can transform your biotransformation studies download the information pack today.
Electron-Activated Dissociation (EAD) is transforming the fields of metabolomics and lipidomics by providing enhanced fragmentation techniques that offer deeper insights into molecular structures. In September, Technology Networks hosted a webinar, “Enhancing Mass-Based Omics Analysis in Model Organisms,” featuring Dr. Valentina Calabrese from the Institute of Analytical Sciences at the University of Lyon. Valentina shared her insights on improving omics-based mass spectrometry analysis for toxicology studies using model organisms, particularly in metabolomics and lipidomics. This blog explores the additional functionalities EAD offers, its benefits in untargeted workflows, its incorporation into GNPS and molecular networking, and the future role it could play in these scientific domains.
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has gained significant attention in the clinical laboratory due to its ability to provide best-in-class sensitivity and specificity for the detection of clinically relevant analytes across a wide range of assays. For clinical laboratories new to LC-MS/MS, integrating this technology into their daily routine operations may seem like a daunting task. Developing a clear outline and defining the requirements needed to implement LC-MS/MS into your daily operations is critical to maximize the productivity and success of your clinical laboratory.
In today’s rapidly evolving food industry, the role of food testing laboratories has never been more critical. Ensuring the safety, quality, and authenticity of food products is paramount, and this responsibility falls heavily on the shoulders of laboratory managers. The economics of food testing—encompassing everything from high-throughput pesticide screening to advanced research on alternative protein sources—plays a pivotal role in shaping the operational efficiency and financial health of these laboratories.
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