GEN-MKT-18-7897-A
Jun 5, 2017 | Blogs, Pharma | 0 comments
If you work in the breakneck world of therapeutic development, then you probably don’t even have time to read this blog (but we thought we would write it anyways, just in case). Drug metabolism samples are coming into your lab fast and furious. You need to turn them around in hours so that chemists and biologists can optimize the effectiveness of the therapeutic candidate. Time for lunch? We don’t think so!
The chances are that you know about high-throughput LC-MS techniques, you probably even know that you need to adopt them, but where do you start? We know how demanding routine biotransformation studies can be, so we have done our best to make this as easy for you as possible with a solution that came from very clear objectives.
We wanted to help you maximize compound analysis while reducing method development time. We wanted to impress you with fast, automated data processing to identify the top metabolites and soft spots. We wanted to give you absolute confidence in the data report, and in a format that a medicinal chemist would like to see. We wanted to give you assurances in instrument uptime so you can just focus on getting the answers you need. We wanted you to have time for lunch!
We bring you the Routine Biotransform Solution, a simple and streamlined platform for high-throughput MetID analyses for both small and large molecule therapeutics. The compact, easy-to-use instrumentation and powerful automated data processing software helps you achieve new levels of productivity and throughput to boost performance and keep your projects moving.
We have crammed in as much of our best-in-class LC-MS technology as we possibly can, making routine ID of the top metabolites and biotherapeutic catabolites as simple and fast as possible. Fully integrated into one complete solution, you benefit from:
We know it is a lot to take in, but if you need high-throughput, then you need a solution as powerful as the Routine Biotransform Solution from SCIEX. For further information on how you can transform your biotransformation studies download the information pack today.
Trifluoroacetic acid (TFA) is emerging as one of the most concerning ultrashort-chain PFAS in Europe’s food supply – particularly in cereals, a staple consumed daily by millions. A report from PAN Europe reveals a widespread and largely unmonitored contamination trend that raises serious questions about food safety, regulatory blind spots, and future monitoring strategies.
PFAS analysis is complex, but expert guidance doesn’t have to be. In this episode of our ‘Ask the PFAS expert series’, we’re joined by Michael Scherer, Application Lead for Food and Environmental, to answer the most pressing questions in PFAS analysis. From why LC-MS/MS systems are the gold standard for analyzing diverse PFAS compounds, to which EU methods deliver reliable results for drinking water, and to practical steps to prevent contamination, Michael shares actionable insights to help laboratories achieve accuracy, consistency, and confidence in their workflows.
During an LC-MS/MS experiment, traditional fragmentation techniques like collision-induced dissociation (CID) have long been the gold standard. Electron-activated dissociation (EAD) is emerging as a transformative tool that enhances structural elucidation, particularly for complex or labile metabolites.
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