GEN-MKT-18-7897-A
Jun 5, 2017 | Blogs, Pharma | 0 comments
If you work in the breakneck world of therapeutic development, then you probably don’t even have time to read this blog (but we thought we would write it anyways, just in case). Drug metabolism samples are coming into your lab fast and furious. You need to turn them around in hours so that chemists and biologists can optimize the effectiveness of the therapeutic candidate. Time for lunch? We don’t think so!
The chances are that you know about high-throughput LC-MS techniques, you probably even know that you need to adopt them, but where do you start? We know how demanding routine biotransformation studies can be, so we have done our best to make this as easy for you as possible with a solution that came from very clear objectives.
We wanted to help you maximize compound analysis while reducing method development time. We wanted to impress you with fast, automated data processing to identify the top metabolites and soft spots. We wanted to give you absolute confidence in the data report, and in a format that a medicinal chemist would like to see. We wanted to give you assurances in instrument uptime so you can just focus on getting the answers you need. We wanted you to have time for lunch!
We bring you the Routine Biotransform Solution, a simple and streamlined platform for high-throughput MetID analyses for both small and large molecule therapeutics. The compact, easy-to-use instrumentation and powerful automated data processing software helps you achieve new levels of productivity and throughput to boost performance and keep your projects moving.
We have crammed in as much of our best-in-class LC-MS technology as we possibly can, making routine ID of the top metabolites and biotherapeutic catabolites as simple and fast as possible. Fully integrated into one complete solution, you benefit from:
We know it is a lot to take in, but if you need high-throughput, then you need a solution as powerful as the Routine Biotransform Solution from SCIEX. For further information on how you can transform your biotransformation studies download the information pack today.
The Echo® MS+ system is a novel platform for Acoustic Ejection Mass Spectrometry (AEMS) and combines the speed of acoustic sampling with the selectivity of mass spectrometry. This platform has been designed for high throughput analysis of small and large molecules. The technology combines Acoustic Droplet Ejection (ADE), an Open Port Interface (OPI) and could be coupled with the SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system.
The Echo® MS+ system comprises of an open-port interface (OPI) and acoustic droplet ejection (ADE) module which could be coupled with a mass spectrometer. The mass spectrometer could either be a SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system. This non-liquid chromatography based; high-throughput screening platform enables rapid analysis of compounds at speeds of up to 1 sample/second.
The ability to consistently achieve reproducible results on many complex samples across multiple days is critical to a routine clinical laboratory. Laboratories relying on analytical instrumentation require stability and robustness to perform a variety of screening and confirmatory assays with confidence. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the preferred analytical method in the clinical laboratory to reliably perform clinical testing as it provides best-in-class performance and reliability for the most challenging assays. LC-MS/MS offers the required levels of sensitivity and specificity for the detection and quantitation of molecules from complex biological samples, helping laboratories deliver highly accurate data for a variety of clinically relevant analytes across a wide range of assays.
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