GEN-MKT-18-7897-A
Jun 19, 2017 | Biopharma, Blogs | 0 comments
Get to know how CESI-MS will allow you to quickly and accurately characterize protein therapeutics for attributes in a single method by downloading this discovery kit.The Biologics Characterization and Discovery Kit Includes:
A Unified Workflow for Monoclonal Antibody Charge Heterogeneity Purity, and Molecular Weight AnalysesDiscover how combining the unique separation capabilities of capillary zone electrophoresis (CZE) with the advantages of an MS-based detector provide high-resolution structural information and accurate molecular weight information. Using CESI-MS and stand-alone CE functionality of the CESI 8000 Plus system, researchers demonstrate powerful methods to characterize intact and reduced IgG forms.
CESI-MS Comparison of Tryptic Digests from Different Monoclonal Antibodies in an Assessment of BiosimilarityIncludes a summary of work recently published by the research group LSMIS at the University of Strasbourg. It focuses on how CESI-MS can be used to characterize and compare a marketed reference mAb with other biosimilar candidates. A CESI-MS protocol for biosimilarity studies of mAbs has been developed which highlights 100% amino acid sequence coverage & PTM “hot spot” mapping and ID.
Structural Characterization of Antibody-Drug Conjugates (ADCs) by a Combination of Intact, Middle-up and Bottom-up Approaches using CESI-MSThis tech note also summarizes work recently published by the research group at LSMIS. In this tech note, discover how CESI-MS can be used to characterize a gold standard cysteine-linked ADC, brentuximab vedotin. Want to learn more about highlighting DAR calculation under native conditions; drug distribution, drug location, 100% coverage and PTMs? It’s all here.
Visit our website to learn more about CE instruments >
In your lab, time is not just a resource. It’s a necessity and every moment counts. Yet, unplanned downtime can disrupt this delicate balance. Even a brief interruption can set your team back in multiple ways.
In a recent webinar, which is now available on-demand, Holly Lee powerful strategies to tackle complex residue testing. From boosting throughput to fine-tuning method sensitivity, Holly shared key ways to maximize performance across large pesticide panels.
Whether we are raising glasses of rosé in a vineyard in France or enjoying a lager in a casual street restaurant in China, it is likely that the last thing on many people’s minds is the chemical risks from their beverage. Unless you work in food science, then it might actually be the first thing.
Posted by
You must be logged in to post a comment.
Share this post with your network