What are my normalization options in MarkerView software and when should I use them?
In an LC-MS experiment there are multiple sources of variance that can confound the quality of your results. This variation can be biological e.g. differences between treated and control groups, but can also be non-biological, usually from small variations in...
How does metadata persist from the Analyst software batch into MarkerView software?
Did you know that MarkerView software can pull information directly from the metadata of your sample datafiles that can help with downstream data processing? To facilitate this, when building your batch in Analyst software, make sure to define your experimental groups...
What is the t-test and when should I use it?
A t-test (sometimes called Student’s t-test) is used to determine if the means of two sample groups are significantly different. So, for LC-MS data, we would typically use a t-test to find out if the amount of our variable of interest (protein, peptide, small...