GEN-MKT-18-7897-A
Jun 3, 2016 | Blogs, Forensic | 0 comments
The importance of protecting a country’s border is a very topical issue. The war on drugs and terror is a 24/7 task 366 days a year (2016 is a leap year). The government agencies in charge must be vigilant and maintain instrumentation to prevent terrorism, drug trafficking, and other illegal activities. Mass Spectrometry is rapidly becoming the instrument of choice for border agencies throughout the world when it comes to explosive trace detection and forensic drug compounds.
In a recent paper in the Journal of Forensic Science1, a comprehensive evaluation using Mass Spectrometry for the trace detection of 2,4,6-trinitrotoluene, C-4, Semtex-H, Datasheet, and HMTD was conducted.
The technology employed in this study was a SCIEX API 3200™ System Mass Spectrometer coupled with the Scentinel system, a thermal desorption and atmospheric pressure chemical ionization (APCI) source, engineered by the trace forensic analysis experts at Mass Spec Analytical based in Bristol, United Kingdom. The unique feature of this technique is that it is a chromatography-free analytical solution. There is no need for intensive sample prep or LC gradient. The sample is introduced to the source and produces a response in a very short period. The findings of this evaluation concluded that,“The direct analysis by mass spectrometry using the Scentinel transformed the traditional day-long quantification analysis of solvent extraction chromatography to minutes, eliminated sample loss, and allowed the transfer efficiency to be quantified for every test surface used.”
The Canadian Border Service Agency (CBSA) requirement for testing explosives detectors is just one such application that could be carried out using this configuration. For more information on the forensic drug screening visit SCIEX.com and discover more about the forensic drug screening services from Mass Spec Analytical.
The latest solution for forensic analyte testing from SCIEX is the X500R QTOF System, an instrument that has been specifically engineered based on the requirements of forensic scientists throughout the world. To accompany the SCIEX OS software we have produced a comprehensive acquired High-Resolution Mass Spec Library, click here for more information about a free trial and XIC list.
1.Tam, M.; Pilon, P. and Zaknoun, H. of the Canadian Border Services Agency (CBSA) entitled “Quantified explosives transfer on surfaces for the evaluation of trace detection equipment”
For research use only. Not for use in diagnostic procedures.
Produced by certain moulds, thriving in crops such as grain, nuts and coffee, mycotoxins have contaminated agriculture and food production industries for a long time. To intensify the challenge, mycotoxins are resilient, not easily broken down and ensuring the safety of food supply chains requires comprehensive solutions and we are here to share those solutions with you.
Electron-Activated Dissociation (EAD) is transforming the fields of metabolomics and lipidomics by providing enhanced fragmentation techniques that offer deeper insights into molecular structures. In September, Technology Networks hosted a webinar, “Enhancing Mass-Based Omics Analysis in Model Organisms,” featuring Dr. Valentina Calabrese from the Institute of Analytical Sciences at the University of Lyon. Valentina shared her insights on improving omics-based mass spectrometry analysis for toxicology studies using model organisms, particularly in metabolomics and lipidomics. This blog explores the additional functionalities EAD offers, its benefits in untargeted workflows, its incorporation into GNPS and molecular networking, and the future role it could play in these scientific domains.
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has gained significant attention in the clinical laboratory due to its ability to provide best-in-class sensitivity and specificity for the detection of clinically relevant analytes across a wide range of assays. For clinical laboratories new to LC-MS/MS, integrating this technology into their daily routine operations may seem like a daunting task. Developing a clear outline and defining the requirements needed to implement LC-MS/MS into your daily operations is critical to maximize the productivity and success of your clinical laboratory.
Posted by
You must be logged in to post a comment.
Share this post with your network