GEN-MKT-18-7897-A
Dec 16, 2016 | Blogs, Food / Beverage | 0 comments
There is nothing like the flavor of fruit juice whether freshly squeezed or made from concentrate to clench your thirst, except when it’s not 100 percent juice after all. As the following tech note, “Authenticity Assessment of Fruit Juices using LC-MS/MS and Metabolomic Data Processing,” (pgs.135-141) points out, such substances have become a likely target for fraud and adultery practice even though certain legislation measures dictate authenticity parameters.
Why should we care? Consumers love to buy fruit juice. In a report by New Scientist, Britain sells more than 800 million pounds per year, while the U.S. holds it stakes at $12 billion or 7.5 billion pounds. Important numbers since 16 out of 21 brands of orange juice sold in Britain contained false ingredients such as beet sugar.Download The Food Compendium >
The problem with existing methods, however, is they are limited to targeted approaches useful when testing one or a handful of adulterations and researchers need to cast a wider net to keep up with the numerous compounds being added to the products. Using LC-MS/MS techniques with the QTRAP® and TripleTOF® systems researchers were able to capture non-targeted results for proof of authenticity. Included in the application note are details right down to where the juices were purchased to sample prep and results.
Why download the compendium? Gain access to almost 200 pages and 18 application methods that respond to real world problems like the ones discussed here. For example, how will you bring these solutions into your lab and improve upon current testing methods? Branch out with new and improved methods you can only find here. It’s just one way you can help prevent the food fraudulence.
In monoclonal antibody (mAb) development, assessment of purity and integrity of the protein in question is critical. CE‑SDS is the gold standard assay and is routinely run from analytical development through QC and lot release. It’s trusted because it consistently delivers quantitative, size‑based insight into purity and fragmentation, and it fits naturally into regulated environments.
In drug discovery and development, Metabolite Identification (Met ID) plays a critical role in understanding biotransformation pathways, ensuring safety, and meeting regulatory requirements. Advanced mass spectrometry techniques have revolutionized this process, particularly through electron-based fragmentation methods such as Electron Activated Dissociation (EAD) and Electron Transfer Dissociation (ETD). While both techniques leverage electron interactions to generate informative fragment ions, they differ significantly in mechanism, performance, and suitability for Met ID workflows.
In analytical laboratories, performance is not optional. Whether supporting regulated pharmaceutical workflows, high-throughput CRO operations, clinical reporting, or food and environmental testing, your mass spectrometry and capillary electrophoresis systems are critical to productivity, compliance, and scientific confidence.
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