GEN-MKT-18-7897-A
Dec 16, 2016 | Blogs, Food / Beverage | 0 comments
There is nothing like the flavor of fruit juice whether freshly squeezed or made from concentrate to clench your thirst, except when it’s not 100 percent juice after all. As the following tech note, “Authenticity Assessment of Fruit Juices using LC-MS/MS and Metabolomic Data Processing,” (pgs.135-141) points out, such substances have become a likely target for fraud and adultery practice even though certain legislation measures dictate authenticity parameters.
Why should we care? Consumers love to buy fruit juice. In a report by New Scientist, Britain sells more than 800 million pounds per year, while the U.S. holds it stakes at $12 billion or 7.5 billion pounds. Important numbers since 16 out of 21 brands of orange juice sold in Britain contained false ingredients such as beet sugar.Download The Food Compendium >
The problem with existing methods, however, is they are limited to targeted approaches useful when testing one or a handful of adulterations and researchers need to cast a wider net to keep up with the numerous compounds being added to the products. Using LC-MS/MS techniques with the QTRAP® and TripleTOF® systems researchers were able to capture non-targeted results for proof of authenticity. Included in the application note are details right down to where the juices were purchased to sample prep and results.
Why download the compendium? Gain access to almost 200 pages and 18 application methods that respond to real world problems like the ones discussed here. For example, how will you bring these solutions into your lab and improve upon current testing methods? Branch out with new and improved methods you can only find here. It’s just one way you can help prevent the food fraudulence.
In biopharmaceutical development, sequence variants (SV) are considered an inherent risk of producing complex proteins in living systems. Sequence variants are unintended changes to the amino acid sequence of a biotherapeutic and can be caused by errors in transcription or translation in the host cell, or cell culture and process conditions. Detailed analysis of SVs is important in process and product development to ensure the drug’s safety and efficacy. Even low‑level sequence variants can have significant implications for product quality, safety, and efficacy, making their accurate detection and characterization a critical requirement across development, process optimization, and regulatory submission.
CE‑SDS remains a cornerstone assay for characterizing fragmentation, aggregation, and product‑related impurities in therapeutic proteins. UV detection has been the long‑standing standard. However, it frequently struggles with baseline noise, limited sensitivity for minor fragments, and subjective integration.
At SCIEX, innovation doesn’t stop at instruments; it extends to how you interact with your LC-MS/MS or CE systems every day. That’s why we’re excited to introduce the SCIEX Now spring 2026 improvements: a set of meaningful enhancements shaped directly by your feedback.
Posted by
You must be logged in to post a comment.
Share this post with your network