GEN-MKT-18-7897-A
Aug 4, 2023 | Blogs, Echo® MS+ system, Pharma | 0 comments
Read Time: 2 minutes
Bringing a new drug to market is a costly and complex process. With potentially hundreds of thousands of new compounds to screen during drug discovery, sample throughput is a common bottleneck for pharmaceutical companies. So how do you overcome this barrier?
The challenges Let’s dig a little deeper into some of the related organizational challenges. On average, the development time for a new drug is 10–15 years, and Deloitte recently reported that the average cost of approving a new pharmaceutical for clinical use rose to $2.3 billion in 20221. Since approximately 90% of new drug candidates fail during development, the ability to make early, informed and accurate decisions about the safety and efficacy of new leads is key to saving time, reducing costs and maximizing success.
The solution The Echo® MS system, which can provide accurate mass spectrometry data in seconds, can help ease these challenges. Based on Acoustic Ejection Mass Spectrometry (AEMS), this system removes the need for chromatographic separation, which increases analytical speed without compromising data quality.
This free infographic explores the concepts of AEMS-based workflows, and the benefits of using this approach for efficient and rapid lead optimization of drug candidates. For example:
Curious to know more? Learn more by exploring the following content, where data from the instrument is used to demonstrate what the system offers.
Rapid MS/MS analysis with Acoustic Ejection Mass Spectrometry (AEMS)
The Echo® MS system from SCIEX breaks through bottlenecks in quantitative mass spectrometry throughput. This technical note describes a rapid, chromatography-free approach to MS/MS analysis and showcases the potential of AEMS to dramatically change the field of high-throughput analysis.
High-throughput metabolite quantification for synthetic biology
This technical note shares a quantitative approach for the screening of 90 yeast strains to monitor over 60 metabolites. This workflow demonstrates the ability of the Echo® MS system to rapidly screen a biological matrix for key metabolites of interest with significantly reduced analysis times.
References
Echo® and Echo® MS are trademarks or registered trademarks of Labcyte, Inc. in the United States and other countries, and are being used under license.
Regulated laboratories are evolving faster than ever. New analytical modalities, higher sample throughput, increasing regulatory scrutiny, and leaner teams are reshaping how work gets done. At the same time, expectations for data integrity, standardization, and operational efficiency continue to increase complexity and/or scope. In this environment, LC-MS software is no longer simply an instrument control platform—it has become a critical part of a laboratory’s quality management system. The question is no longer whether your lab has changed, but whether your software has evolved to support the way regulated labs operate today, and if they are ready and able to meet the demands, they will face tomorrow.
Analyst software has long been a trusted foundation in regulated LC-MS laboratories—and for many, it still performs reliably today. But regulated environments are evolving faster than ever. As labs transition to Windows 11, strengthen cybersecurity policies, modernize IT infrastructure, and prepare for future compliance expectations, software decisions are no longer just about what works today—they’re about managing tomorrow’s risk. Analyst will not be supported on Windows 11. While some labs may continue operating in unsupported environments temporarily, the bigger question is: when that risk becomes reality, will your lab be reacting under pressure—or executing a planned mitigation strategy with confidence?
As regulatory scrutiny increases and detection requirements tighten, laboratories are facing a new question: How can TFA be measured reliably, sensitively, and at scale?
Posted by
You must be logged in to post a comment.
Share this post with your network