Selecting an LC-MS system for quantitation of pharmaceutical drug development

Oct 29, 2024 | Blogs, Echo® MS+ system, Pharma, QTRAP / Triple Quad, ZenoTOF 7600 system | 0 comments

Read time: 2 minutes

Introduction

Drug development is a challenging process that requires diverse analytical solutions and the expertise of research scientists.

 

Within drug discovery confident go/no-go decisions need to be made as quickly as possible. Often, highly sensitive techniques are needed to accurately monitor concentrations of biomarkers, therapeutic candidates, and their metabolites. QA/QC laboratories need consistent performance everyday over many years.

 

Pharmaceutical quantitation solution guide

We understand you are busy, needing to prioritize running instruments, reporting results and managing your laboratory to meet deadlines. We created a solution guide to explain how SCIEX systems fit in the drug development pipeline to save you time evaluating options.

 

The guide covers bio/pharmaceutical quantitative assays from discovery to QA/QC, for large and small molecules.  Discussing challenges regularly faced by scientists, along with potential solutions.

 

Download the guide >

 

What’s inside the guide?

The guide includes comprehensive chapters addressing multiple challenges and solutions regularly faced in drug development.

 

Discovery

  • Identify hits with accuracy and speed
  • Easily report results with end-to-end workflows
  • Measure molecular masses for small and large drug candidates

 

Development (Small and large molecules)

  • Acquire reliable and sensitive bioanalytical data
  • Perform studies with confidence using compliance-ready software
  • Get support from a team of dependable experts

 

Regulatory solutions

  • Minimize regulatory risk with complete system solutions
  • Ensure compliance for instruments through installation and maintenance qualifications
  • Reduce human error with user access levels

 

QA/QC and lot release

  • Quickly identify deviations from product specifications
  • Flexible system configurations that can be tailored to an ever-evolving regulatory landscape
  • Expert application and service support

 

Products

  • Discover systems at the forefront of quantitative performance
  • Benefit from compliance-ready software and trusted service partners
  • Ensure your results are the best they can be

 

Download the guide here >

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As PFAS testing continues to expand, laboratories face increasing pressure to deliver reliable results at lower detection limits and faster turnaround times. While much of the conversation focuses on analytical methods and regulations, maintaining instrument performance and minimizing downtime are equally critical to success.

How LC-MS laboratories in regulated environments can build a strong foundation for reliable data, audit readiness and lifecycle control

Whether supporting pharmaceutical quality control, bioanalysis, clinical research, environmental testing, or food safety applications, regulated laboratories share a common responsibility: ensuring reliable data, maintaining audit readiness, and controlling systems throughout their lifecycle. Yet when compliance discussions arise, attention often moves quickly to audits, documentation, electronic records, and standard operating procedures. These elements are essential, but they depend on a more fundamental question: Can the analytical system consistently produce reliable results?

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