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Drug Metabolism and Bioanalysis Journal Articles Focus on Drug Metabolism and so Much More

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Check-out the top articles that focus on innovations in drug metabolism as well as small molecule quantitation and biologics bioanalysis. Exciting advancements! We can’t wait to see all that will come in 2016!

  1. Quantitative analysis of maytansinoid (DM1) in human serum by on-line solid phase extraction coupled with liquid chromatography tandem mass spectrometry – Method validation and its application to clinical samples
  2. Quantitative bioanalysis of antibody-conjugated payload in monkey plasma using a hybrid immuno-capture LC–MS/MS approach: Assay development, validation, and a case study
  3. An integrated multiplatform bioanalytical strategy for antibody–drug conjugates: a novel case study
  4. Accurate and sensitive liquid chromatography/tandem mass spectrometry simultaneous assay of seven steroids in monkey brain
  5. Quantitative analysis of intracellular nucleoside triphosphates and other polar metabolites using ion pair reversed-phase liquid chromatography coupled with tandem mass spectrometry
  6. Comprehensive Characterization of Low Molecular Weight Heparins Using High-Resolution Mass Spectrometry
  7. Quantitative Analysis of Transporter Protein using TripleTOF® 6600 System
  8. Trends in Bioanalysis Using LC–MS–MS
  9. Comprehensive characterization of protein therapeutics using CESI, exceptional resolution combined with MS
  10. Identification of metabolites of oridonin in rats with a single run on UPLC-Triple-TOF-MS/MS system based on multiple mass defect filter data acquisition and multiple data processing techniques
  11. Rapid identification of efavirenz metabolites in rats and humans by ultra-high performance liquid chromatography combined with quadrupole time-of-flight tandem mass spectrometry
  12. Software automation tools for increased throughput metabolic soft-spot identification in early drug discovery
  13. Metabolite profiles of icariin in rat plasma by ultra-fast liquid chromatography coupled to triple quadrupole/time-of-flight mass spectrometry
  14. Comparison of Information-Dependent Acquisition, SWATH, and MSAllTechniques in Metabolite Identification Study Employing Ultrahigh-Performance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry
  15. High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis
  16. Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle
  17. Quantitation of Insulin Analogue Glargine and Its Two Metabolites M1 and M2 on Triple Quad 6500 and Triple TOF 5600 LC-MS/MS Systems in a Dog Toxicokinetics Study
  18. Performance enhancement in the measurement of 5 endogenous steroids by LC-MS/MS combined with differential ion mobility spectrometry
  19. Differential Mobility Separation of Leukotrienes and Protectins
  20. Rapid Quantification of Digitoxin and Its Metabolites Using Differential Ion Mobility Spectrometry-Tandem Mass Spectrometry

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