GEN-MKT-18-7897-A
Aug 22, 2016 | Blogs, Food / Beverage | 0 comments
Quantitating antibiotics and insecticides in poultry is serious business. Overuse can lead to antibiotic resistance while insecticide residuals can cause harmful side effects in humans. In the United States, for example, the Federal Drug Administration (FDA), has offered up a plan to limit common antibiotics in feed, which are used to encourage growth. However, this is a voluntary plan, and as the following application note, “Quantitation of Antibiotics and Insecticides in Poultry Feed using LC-MS/MS,” points out, antibiotics have been shown to accumulate in poultry feathers, which are in turn used for nutritional elements in the feed. Therefore, as the government agency works on getting suppliers on board with the new plan, scientists are working on a testing method of their own which detects nine antibiotics and four insecticides in poultry feed including:
Perhaps you have seen this study, but just in case you missed it, we have included the full report in the Food & Beverage Compendium, which is now available for download.Download the Food & Bev Compendium >
Application Note at a Glance: To give you more insight into this application note and others like it in the compendium, consider how poultry feed contains many nutritional ingredients. Researchers had to design a method that included a hefty extraction method and clean-up efforts. As a result, they designed a single method to quantify a wide selection of antibiotics and insecticides in poultry feed using a QTRAP® 5500 for detection. Want to see how the extraction/sample prep was carried out? These experimental conditions along with separation and MS/MS detection are included within the compendium (pages 121 to 125).
The Food & Beverage Compendium is full of similar studies on topics including:
Discover where science is taking Food and Beverage with this FREE, and Informative Compendium.
The Echo® MS+ system is a novel platform for Acoustic Ejection Mass Spectrometry (AEMS) and combines the speed of acoustic sampling with the selectivity of mass spectrometry. This platform has been designed for high throughput analysis of small and large molecules. The technology combines Acoustic Droplet Ejection (ADE), an Open Port Interface (OPI) and could be coupled with the SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system.
The Echo® MS+ system comprises of an open-port interface (OPI) and acoustic droplet ejection (ADE) module which could be coupled with a mass spectrometer. The mass spectrometer could either be a SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system. This non-liquid chromatography based; high-throughput screening platform enables rapid analysis of compounds at speeds of up to 1 sample/second.
The ability to consistently achieve reproducible results on many complex samples across multiple days is critical to a routine clinical laboratory. Laboratories relying on analytical instrumentation require stability and robustness to perform a variety of screening and confirmatory assays with confidence. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the preferred analytical method in the clinical laboratory to reliably perform clinical testing as it provides best-in-class performance and reliability for the most challenging assays. LC-MS/MS offers the required levels of sensitivity and specificity for the detection and quantitation of molecules from complex biological samples, helping laboratories deliver highly accurate data for a variety of clinically relevant analytes across a wide range of assays.
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