Metabolism and Biotransformation – What Are You Missing?

Jul 26, 2018 | Blogs, Pharma | 0 comments

Are you looking to improve your MetID studies? Want to achieve the productivity and throughput you need to keep your projects moving and have complete confidence that you’re not missing any low level or parent-like metabolites in your sample? In this blog, we’re bringing you the highlights from the recently released Metabolism and Biotransformation Application eBook. This eBook is packed with solution guides, webinars, videos, bulletins, and other resources.

What are Metabolism and Biotransformation Solutions?
Biotransformation studies in discovery and development present their own unique challenges. During discovery, workflows can be hindered by complex hardware and sluggish software that may struggle to handle complex therapeutics or require extensive manual interpretation. In development, the possibility of missing low level or toxic metabolites is a huge risk, not to mention cumbersome data processing that can be required, especially for analysis of large molecule therapeutics. In recognition of these challenges, we’ve developed two integrated solutions to streamline your routine and advanced biotransformation studies so you can get confident answers as efficiently as possible. The eBook expands on these solutions for your lab.

How Can You Speed High-Throughput MetID Analyses?
The Routine Biotransform Solution offers a simple and streamlined platform for high-throughput MetID analyses for both small and large molecule therapeutics. This solution is for you if you need to maximize compound analysis, reduce method development time, and automate data processing to identify the top metabolites and soft spots. Fully integrated into one complete solution, with the easy-to-use X500R QTOF system and intuitive SCIEX OS user interface, we have made MetID as simple and fast as possible for the top metabolites and biotherapeutic catabolites.

How Can You Achieve Comprehensive Metabolite ID?
The Advanced Biotransform Solution is designed for pushing the limits of metabolite and biotherapeutic catabolite identification. If you need to advance new drugs through metabolism studies in the development pipeline with the most advanced, integrated solution available on the market, you’ll want to try this solution. You get maximum sensitivity and dynamic range for low-level metabolite ID using the Triple TOF 6600 system with ultra-fast and unbiased SWATH® Acquisition. You can be confident you are acquiring high-quality data on all detectable metabolites in your sample; nothing hides from this solution.

I’m Still Not Convinced, What Else Can You Offer?
Well if that isn’t enough, we integrated our industry-leading MetabolitePilot™ Software 2.0 for small molecule metabolite identification and large molecule catabolite investigation. Now you can take your biologic data processing beyond laborious manual spreadsheets and accelerate it with fully automated analysis and reporting. 

Why Should I Download This eBook?
Download the Metabolism and Biotransformation Application eBook today and learn how to transform your metabolism studies. Achieve the throughput you need to keep your projects moving and have complete confidence that you’re not missing any low level or parent-like metabolite in your sample. Now you know what you are missing, what are you waiting for?

Ready to speak to an expert about implementing this solution in your lab? Comment below, and we’ll set you up with a technical specialist.

 

How SCIEX Now empowers mass spec users to work with more control, clarity and confidence

In this interview, Andy Wilcox, Senior Market Development Manager, Aftermarket and Software, speaks with Susanna Baqué, Senior Director of Global Customer Experience, about how SCIEX Now gives customers one connected digital workspace to manage instruments, reduce time spent searching for information, resolve issues faster and keep their laboratory running more efficiently and with greater confidence.

Bioanalysis across modalities: Advancing confident decisions with modern LC‑MS strategies

As therapeutic pipelines continue to diversify, bioanalysis is being asked to do more than ever before. From small molecules to complex biologics, today’s scientists must generate high‑quality, reliable data across a growing range of molecule types and workflows, often under increasing time pressure.

The rules have changed

Regulated laboratories are evolving faster than ever. New analytical modalities, higher sample throughput, increasing regulatory scrutiny, and leaner teams are reshaping how work gets done. At the same time, expectations for data integrity, standardization, and operational efficiency continue to increase complexity and/or scope. In this environment, LC-MS software is no longer simply an instrument control platform—it has become a critical part of a laboratory’s quality management system. The question is no longer whether your lab has changed, but whether your software has evolved to support the way regulated labs operate today, and if they are ready and able to meet the demands, they will face tomorrow.

Posted by

0 Comments

Submit a Comment

Pin It on Pinterest

Share This

Share this post with your network