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New EPA Method 563: Taking on the challenge of ultrashort-chain PFAS


 PFAS testing is entering a new phase. With seven ultrashort-chain organofluorine compounds included in EPA Method 563, drinking water laboratories face a new set of analytical challenges, from poor chromatographic retention and background contamination to limited fragmentation.

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November 9, 2026


PFAS FAQ’s: Ask our experts


As PFAS testing continues to expand, laboratories face increasing pressure to deliver reliable results at lower detection limits and faster turnaround times. While much of the conversation focuses on analytical methods and regulations, maintaining instrument performance and minimizing downtime are equally critical to success.

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November 2, 2026


How LC-MS laboratories in regulated environments can build a strong foundation for reliable data, audit readiness and lifecycle control


Whether supporting pharmaceutical quality control, bioanalysis, clinical research, environmental testing, or food safety applications, regulated laboratories share a common responsibility: ensuring reliable data, maintaining audit readiness, and controlling systems throughout their lifecycle. Yet when compliance discussions arise, attention often moves quickly to audits, documentation, electronic records, and standard operating procedures. These elements are essential, but they depend on a more fundamental question: Can the analytical system consistently produce reliable results?

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October 28, 2026


Future-proofing pesticide testing: Why speed is becoming a competitive advantage


Food testing laboratories face growing pressure. Pesticide panels continue to expand, regulations evolve, and customers still expect fast turnaround times at a competitive cost.

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October 20, 2026


Celebrating customer experience: Insights from SCIEX leaders


Customer Experience Day (CX Day) is a special occasion for SCIEX, celebrated every first Tuesday in October. It’s a day dedicated to recognizing the incredible value of our customers and the relentless dedication of our associates who strive to make every interaction meaningful. At SCIEX, our commitment to customer experience is woven into the fabric of everything we do. From providing cutting-edge solutions to offering unwavering support, we aim to build lasting relationships and exceed expectations. Join us as we delve into the insights from our leaders on what customer experience means to SCIEX and how it shapes our journey.

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October 1, 2026


Why traditional MS/MS falls short for ADCs and how electron-activated dissociation (EAD) changes the equation


Antibody-drug conjugates (ADCs) are among the most promising—and analytically demanding—modalities in biopharma today. By combining large, heterogeneous antibodies with chemically labile payloads and linkers, ADCs introduce a level of structural complexity that challenges conventional analytical workflows. It also poses the challenge that the very features you need to measure are often the easiest to lose during analysis.

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September 14, 2026


Six benefits of remote support every laboratory should know


Imagine having a tech expert at your fingertips to solve computer issues or a fitness trainer guiding you through workouts from the comfort of your home. In today’s fast-paced world, the ability to provide and receive service and support remotely is no longer a luxury but a necessity. Whether it’s troubleshooting a software issue, repairing a device, offering customer assistance, or enjoying the convenience of telehealth as a private individual, remote capabilities have revolutionized how businesses operate and how individuals get help

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The costly consequences of unplanned downtime


Unplanned downtime is a formidable adversary that businesses across various industries strive to minimize. Defined as the unexpected interruption of regular operations, unplanned downtime can wreak havoc on productivity, profitability and customer satisfaction. In this article, we delve into the causes of unplanned downtime, its far-reaching consequences and strategies to mitigate its impact.

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Why SCIEX partners with experts around the world


Innovation in mass spectrometry does not happen in isolation. Some of the most impactful scientific advances emerge from highly specialized research communities – proteomics experts developing new peptide identification workflows, metabolomics researchers curating spectral databases, toxicologists building compound libraries, and biopharma scientists creating novel characterization methods.

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August 25, 2026


Managing ADC characterization: The challenge of turning complexity into confidence


Unlike traditional monoclonal antibodies, ADCs combine an antibody backbone with linker chemistry and a cytotoxic payload. This multi-component architecture introduces overlapping layers of heterogeneity, including drug-to-antibody ratio (DAR) distributions, charge variants, post-translational modifications, and structural changes at both the intact and subunit levels. Across ADC development, these characteristics are considered critical quality attributes that must be characterized, understood, and monitored.

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