Automatic calibration in minutes for microflow LC with the OptiFlow source on ZenoTOF 7600 system by Alexandra Antonoplis | Aug 7, 2021 | Bioanalysis/PK, Biopharma, Data acquisition, Ion sources, Life Science Research, Metabolomics, Pharma, Proteomics, SCIEX information, Technology, ZenoTOF 7600 systemThe OptiFlow ion source for the SCIEX ZenoTOF 7600 system is equipped with an ESI calibration probe for automatic calibration during microflow experiments (diagram below). The ESI probe is installed orthogonal to the microflow probe in the OptiFlow source and...
What is the Zeno threshold and what does it do? by Robert Di Lorenzo | Aug 7, 2021 | Bioanalysis/PK, Data acquisition, Lipidomics, Metabolomics, Multi-Omics, Proteomics, SCIEX information, SCIEX OS software, Technology, Toxicology, ZenoTOF 7600 systemWith the introduction of the Zeno trap on the ZenoTOF 7600 system, sensitivity improvements on the order of 4 to 25x can be seen for MS/MS analysis, because of the optimization of duty cycle.1 When concentrations are low and peak intensities are limited, this bump in...
Tips and tricks: setting up LC-MS/MS methods for lipid mediator profiling by Mackenzie Pearson | Aug 7, 2021 | Data acquisition, Life Science Research, Lipidomics, Methods / workflows, QTRAP / Triple Quad, SCIEX informationStarting up a workflow for lipid mediator analysis can be challenging. Hundreds of distinct fatty acid-derived molecules can be produced biologically (i.e., enzymatically) and/or via non-enzymatic routes. Additionally, various biosynthetic pathways yield both...
Importing processing methods from Analyst or MultiQuant software to SCIEX OS-MQ software by April Quinn-Paquet | Aug 7, 2021 | Data processing, Getting Started, How-to videos, QTOF, QTRAP / Triple Quad, SCIEX OS software, Technology, ZenoTOF 7600 systemSCIEX OS-MQ software is the latest innovation from SCIEX in fast, reliable data processing and streamlined review. Combining the powerful features of multiple software platforms into one, it’s a single solution for your data processing needs. But you don’t have to...
Guided optimization of MRM by infusion in SCIEX OS software by Christie Hunter | Aug 7, 2021 | Data acquisition, How-to videos, QTRAP / Triple Quad, SCIEX OS software, TechnologyThis short video walks through the use of the automated MRM optimization feature in SCIEX OS software for optimizing the compound dependent parameters for an MRM experiment using an infusion approach. Here, we infuse reserpine to demonstrate the key elements of MRM...