sMRM Pro Builder template tutorial

sMRM Pro Builder template tutorial

The sMRM Pro Builder template is an Excel-based tool that can help you implement large panels of analytes in your lab. The Excel sheet will take your preliminary experimental results and compute retention times, retention time window widths and dwell time weighting to...
High level method optimization considerations for Echo MS system

High level method optimization considerations for Echo MS system

While an in-depth discussion of method development and optimization for the Echo® MS system is beyond the scope of a community post, here are some points to consider as part of the process: The maximum recommended ion spray voltage for prolonged electrode life is 5000...
High level method optimization considerations for Echo MS system

What to do if you see peak shape deterioration or jagged peaks in your Echo MS system data?

Once a method has been developed, and good, consistent peak shapes have been obtained for an assay, the Echo® MS system is generally quite consistent. If peak quality deteriorates, consider the following points: The viscosity of the sample can affect the peak shape...
High level method optimization considerations for Echo MS system

Tips to maximize electrode lifetime for Echo MS system

While it’s easy to think of the Echo® MS system as an ultrafast LC system in front of the SCIEX Triple Quad 6500+ mass spectrometer, the system operates on fundamentally different principles. For this reason, it requires different routine maintenance to keep it...