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Meeting deadlines in a bioanalysis laboratory can be a big challenge. Older, less sensitive and less reliable LC-MS systems make it even more difficult. Even the disruption caused by the installation and validation can be disconcerting and delay decisions. Does this sound familiar?

Let’s break down the process and potential benefits of a regulated laboratory. The biggest challenge is usually the software installation and validation. To streamline this step, the Change Control support plan from SCIEX helps customers who require revalidation of their software to mitigate risk for software and hardware system assessments. Collaborate with us to integrate new software features seamlessly, bolster system security, enhance performance and ensure compatibility.

Is it time … for more reliability?

High system robustness enables analysis of large-scale sample sets

Learn how the robustness of the QTRAP 6500+ system ensures a smooth analysis of gut metabolites in plasma even with a high number of samples, complex matrices and challenging excipients.

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Is it time … for more sensitivity?

Highly sensitive LC-MS/MS method for the quantification of fluticasone propionate in human plasma

Fluticasone propionate, a synthetic glucocorticoid with potent anti-inflammatory activity, requires very sensitive assays to monitor pharmacokinetic parameters due to the very low therapeutic inhaled dose ranges. This need has led us to use large sample volumes. Here, a selective, sensitive and reproducible bioanalytical method was developed for quantitation of fluticasone propionate (LLOQ of 200 fg/mL) in human plasma using the QTRAP 6500 system. Reduced sample volume (500 µL plasma) and a final reconstitution volume of 200 µL for reinjection of samples or repeat analysis chromatography if required in a GLP laboratory.

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Is it time … to reduce operational costs?

SCIEX OS software allows you to upgrade to a dry roughing pump configuration, you can expand your productivity and save money at the same time.

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