Journal publications using the Echo® MS (+) system by Han Wang | Jun 17, 2025 | Blogs, Echo® MS+ system, PharmaThe Echo® MS+ system is a novel platform for Acoustic Ejection Mass Spectrometry (AEMS) and combines the speed of acoustic sampling with the selectivity of mass spectrometry. This platform has been designed for high throughput analysis of small and large molecules. The technology combines Acoustic Droplet Ejection (ADE), an Open Port Interface (OPI) and could be coupled with the SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system.
Technical notes using the Echo® MS+ system by Anuja Bhalkikar | Jun 17, 2025 | Blogs, Echo® MS+ system, PharmaThe Echo® MS+ system comprises of an open-port interface (OPI) and acoustic droplet ejection (ADE) module which could be coupled with a mass spectrometer. The mass spectrometer could either be a SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system. This non-liquid chromatography based; high-throughput screening platform enables rapid analysis of compounds at speeds of up to 1 sample/second.
Methods for electrode cleaning for Echo MS systems by John Gibbons | Jun 3, 2025 | Blogs, Echo® MS+ system, PharmaDepending on the samples that you are running on the system, it is possible for the Echo MS electrode to become dirty or occluded over time. Below are two different cleaning strategies that will be helpful for you to maintain your system and keep your electrodes running well.
Inside the box: Acoustic ejection mass spectrometry for drug discovery by Kirsten Craven | Feb 12, 2025 | Blogs, Discovery, Echo® MS+ system, Pharma, QA/QCOn average, it takes 10-15 years and 1-2 billion dollars to approve a new pharmaceutical for clinical use. Since approximately 90% of new drug candidates fail in clinical development, the ability to make early, informed and accurate decisions on the safety and efficacy of new hits and leads is key to increasing the chances of success.
Selecting an LC-MS system for quantitation of pharmaceutical drug development by Kirsten Craven | Oct 29, 2024 | Blogs, Echo® MS+ system, Pharma, QTRAP / Triple Quad, ZenoTOF 7600 systemWe understand you are busy, needing to prioritize running instruments, reporting results and managing your laboratory to meet deadlines. We created a solution guide to explain how SCIEX systems fit in the drug development pipeline to save you time evaluating options.
Is the next life-changing drug waiting to be analyzed in your laboratory? by Kirsten Craven | Jun 24, 2024 | Blogs, Echo® MS+ system, PharmaIn drug discovery laboratories, there is often a need to generate trusted analytical data on hundreds of thousands of drug candidates to allow confident decisions to be made. Sample prep, instrument run time, and data processing are all challenges that must be overcome.
Data acquisition on the Echo® MS system: post-acquisition file splitting by Anuja Bhalkikar | Sep 14, 2023 | Data acquisition, Echo® MS+ system, SCIEX information, TechnologyThe Echo® MS system is an ultra-high-throughput system that analyzes samples at a speed of up to 1 sample per second. To achieve fast acquisition speeds, MS data is collected for an entire batch—or the entire well plate—into a single experiment in a file....
Want to accelerate your drug discovery workflow? by Kirsten Craven | Aug 4, 2023 | Blogs, Echo® MS+ system, PharmaBringing a new drug to market is a costly and complex process. With potentially hundreds of thousands of new compounds to screen during drug discovery, sample throughput is a common bottleneck for pharmaceutical companies. So how do you overcome this barrier?
Please provide at least 3 decimal places for expected retention time for scheduled MRM at EchoMS by Riyo Imamura | Jun 22, 2023 | Data acquisition, Echo® MS+ system, Questions, SCIEX OS software, TechnologyExpected retention time for scheduled MRM at EchoMS must have at least 3 decimal places, because the minute display with two decimal places is insufficient to show the difference in seconds. Thank you.
Acoustic Ejection Mass Spectrometry at ASMS 2023 by Christie Hunter | Jun 4, 2023 | Echo® MS+ system, SCIEX information, TechnologyFor all those interested in learning about all the cool applications possible with AEMS and the Echo MS system, here is a list of presentations at ASMS 2023. Monday: MOH 3:50pm – Intact protein analysis MP 294 – Metabolite identification MP 312 Compound QC Tuesday TOB...