GEN-MKT-18-7897-A
Dec 1, 2017 | Biopharma, Blogs, Life Science Research | 0 comments
The 2017 Global CESI-MS Symposium brought together KOLs and industry innovators from around the world to share their latest advancements using capillary electrophoresis integrated with electrospray ionization (CESI-MS) within the same device.
Hosted by Dr. Alexander Ivanov at the renowned Barnett Institute on the campus of Northeastern University, the 2017 Global CESI-MS Symposium was held in Boston, Massachusetts, on October 5-6, 2017.
Attendees at the conference heard how industry innovators have revealed hidden information not seen before such as proteoforms and peptides; intact mAb charge variants; native proteins; isobaric metabolites and glycans not resolved by traditional techniques; and charged and polar analytes.
The Symposium was hosted by Professor Alexander R. Ivanov, at the Barnett Institute, on the campus of Northeastern University, with sessions chaired by:
Proteomics and Metabolomics:
Novel and Advanced Applications
Biopharma
In case you were not able to attend or experience the live presentations online, we have made them available on-demand >
Join us next year in The Netherlands! Stay tuned for more information.
In monoclonal antibody (mAb) development, assessment of purity and integrity of the protein in question is critical. CE‑SDS is the gold standard assay and is routinely run from analytical development through QC and lot release. It’s trusted because it consistently delivers quantitative, size‑based insight into purity and fragmentation, and it fits naturally into regulated environments.
In drug discovery and development, Metabolite Identification (Met ID) plays a critical role in understanding biotransformation pathways, ensuring safety, and meeting regulatory requirements. Advanced mass spectrometry techniques have revolutionized this process, particularly through electron-based fragmentation methods such as Electron Activated Dissociation (EAD) and Electron Transfer Dissociation (ETD). While both techniques leverage electron interactions to generate informative fragment ions, they differ significantly in mechanism, performance, and suitability for Met ID workflows.
In analytical laboratories, performance is not optional. Whether supporting regulated pharmaceutical workflows, high-throughput CRO operations, clinical reporting, or food and environmental testing, your mass spectrometry and capillary electrophoresis systems are critical to productivity, compliance, and scientific confidence.
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