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<a href="https://community.sciex.com/author/kelly-may-2/" target="_self">Kelly May</a>

Kelly May

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On Demand Videos from the 2017 Global CESI-MS Symposium

Dec 1, 2017 | Biopharma, Blogs, Life Science Research | 0 comments

Bringing Together KOLs and Scientists from Around the World

The 2017 Global CESI-MS Symposium brought together KOLs and industry innovators from around the world to share their latest advancements using capillary electrophoresis integrated with electrospray ionization (CESI-MS) within the same device.

Hosted by Dr. Alexander Ivanov at the renowned Barnett Institute on the campus of Northeastern University, the 2017 Global CESI-MS Symposium was held in Boston, Massachusetts, on October 5-6, 2017.

Attendees at the conference heard how industry innovators have revealed hidden information not seen before such as proteoforms and peptides; intact mAb charge variants; native proteins; isobaric metabolites and glycans not resolved by traditional techniques; and charged and polar analytes.

The Symposium was hosted by Professor Alexander R. Ivanov, at the Barnett Institute, on the campus of Northeastern University, with sessions chaired by:

Proteomics and Metabolomics:

  • Professor Alexander Ivanov, Northeastern University
  • Professor Jennifer Van Eyk, Cedars Sinai Medical Center, USA

Novel and Advanced Applications

  • Dr. Spencer Walse, USDA-ARS, USA

Biopharma

  • Professor John R. Yates III, The Scripps Research Institute, USA

In case you were not able to attend or experience the live presentations online, we have made them available on-demand >

Watch the Webinars On Demand

Join us next year in The Netherlands! Stay tuned for more information.

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If we lived in an ideal world, it would be possible to unambiguously identify metabolites using a single analytical experiment. This analytical technique would need to be efficient and easily generate the information needed from a routine assay that is also robust, enabling confident decision-making during drug discovery.

Supporting new CRISPR gene editing systems

Prime editing (PE) is a next-generation gene editing technology that utilizes a Cas9 protein fused to a prime editing guide ribonucleic acid (pegRNA) to achieve high CRISPR/Cas9 editing efficiency and precision. However, the length requirement of pegRNAs at 120–250 nucleotides (nt) and their high level of secondary structure formation present analytical challenges for the purity analysis of chemically synthesized pegRNAs during development and quality control (QC).

A new approach for comprehensive AAV evaluation including full and empty analysis

Certain next-gen vaccines and gene therapy applications rely on the usage of adeno-associated viruses (AAV) as a delivery vehicle. To ensure the safety and efficacy of viral vector drugs, multiple critical quality attributes (CQAs) need to be well characterized.

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