Methods for OPI electrode cleaning for Echo® MS system electrodes by Christie Hunter | 1 CommentDepending on the samples you are running on the system, it is possible for the Open Port Interface (OPI) electrode to become dirty or occluded over time. Below are two different cleaning strategies that can help you maintain your Echo® MS system and keep your OPI...
Using Scheduled Ionization to reduce system ion load for proteomics data acquisition by Alexandra Antonoplis | 0 CommentsWhen analyzing highly complex samples from biological matrices, there can be significant amounts of material that elute in the wash cycle of the LC run, depending on the up-front sample preparation used. The Scheduled Ionization mode, available in both SCIEX OS...
Assess the performance of the Echo® MS system by Christie Hunter | 0 CommentsTo obtain the best, most reproducible results using the Echo MS system, it is important to select the best solvent for your analyte and matrix and to ensure the flow rate is optimized for your solvent. Please review this flow rate optimization community post to...
How to optimize sample plating to run Echo MS system in ‘Fast acquisition mode’ by Mackenzie Pearson | 0 CommentsThe Echo MS system can acquire data extremely rapidly, at 1 second per sample. To achieve this speed, it should be ensured that there is adequate time between ejections for the analyte signal to return to baseline between ejections. Plating your samples such that you...
Methods for OPI electrode cleaning for Echo® MS system electrodes by Christie Hunter | Echo MS, Instrument maintenance, SCIEX information, TechnologyDepending on the samples you are running on the system, it is possible for the Open Port Interface (OPI) electrode to become dirty or occluded over time. Below are two different cleaning strategies that can help you maintain your Echo® MS system and keep your OPI...
Using Scheduled Ionization to reduce system ion load for proteomics data acquisition by Alexandra Antonoplis | Data acquisition, Ion sources, Life Science Research, Proteomics, QTOF, QTRAP / Triple Quad, SCIEX information, SCIEX OS software, ZenoTOF 7600 systemWhen analyzing highly complex samples from biological matrices, there can be significant amounts of material that elute in the wash cycle of the LC run, depending on the up-front sample preparation used. The Scheduled Ionization mode, available in both SCIEX OS...
Assess the performance of the Echo® MS system by Christie Hunter | Echo MS, Optimizing Performance, SCIEX information, TechnologyTo obtain the best, most reproducible results using the Echo MS system, it is important to select the best solvent for your analyte and matrix and to ensure the flow rate is optimized for your solvent. Please review this flow rate optimization community post to...
How to optimize sample plating to run Echo MS system in ‘Fast acquisition mode’ by Mackenzie Pearson | Data acquisition, Echo MS, Optimizing Performance, Pharma, SCIEX information, TechnologyThe Echo MS system can acquire data extremely rapidly, at 1 second per sample. To achieve this speed, it should be ensured that there is adequate time between ejections for the analyte signal to return to baseline between ejections. Plating your samples such that you...
How to download and use SVG files from OneOmics suite by Alexandra Antonoplis | Data Visualization, Life Science Research, Multi-Omics, OneOmics, SCIEX informationResults workspaces in the OneOmics suite contain a variety of figures, all available for download as SVG (scalable vector graphic) files. To download your figures, select the orange arrow icon located in the upper right-hand corner of each plot. Download will...
How do I define the experimental design (the metadata) for my SWATH acquisition study within the OneOmics suite? What are the requirement for replicates? by Christie Hunter | Data processing, Life Science Research, Metabolomics, OneOmics, Proteomics, QTOF, SCIEX information, ZenoTOF 7600 systemIn quantitative Omics research, the goal is to understand which analytes (protein or metabolite) are perturbed between experimental conditions; therefore we carefully design our studies to explore these questions. The algorithms used within the Assembler application...
Breaking down the SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP® Ready by Jianru Stahl-Zeng | Blogs, ClinicalSensitivity and robustness carry different meanings in the world of mass spectrometry. Generally, sensitivity refers to an instrument’s ability to achieve lower limits of detection (LOD). Robustness, on the other hand, refers to an instrument’s ability to consistently...
A rising star in food allergen research: proteomics of shellfish allergen by SCIEX Community | Blogs, Food / Beverage, Life Science Research, ProteomicsIt’s important to know what you’re eating, especially if you suffer from a food allergy. About 220 million people worldwide live with a food allergy.1 These numbers, along with the complexity and severity of conditions, continue to rise. In America, there are about 32 million food allergy sufferers—5.6 million of those are children under the age of 18.2.2 That’s 1 out of every 13 children, or about 2 in every classroom. From a financial perspective, the cost of food allergy childcare for US families is up to $25 billion